CD276 - Wikipedia
Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. [5] B7-H3 is a 316 amino acid-long type I transmembrane protein, existing in …
CD276 Gene - GeneCards | CD276 Protein | CD276 Antibody
2024年12月24日 · CD276 (CD276 Molecule) is a Protein Coding gene. Diseases associated with CD276 include Long Qt Syndrome and Glioma Susceptibility 1 . Among its related pathways …
B7-H3, a checkpoint molecule, as a target for cancer …
2022年3月20日 · B7-H3 (also known as CD276) is a newly found molecule of B7 family, which may be a promising target for cancer treatment. B7-H3 protein was demonstrated to be …
The Role of CD276 in Cancers - PubMed
2021年3月26日 · CD276 plays an essential role in cell proliferation, invasion, and migration in malignancies. Results from most recent studies indicate CD276 could be a promising …
New frontiers in immune checkpoint B7-H3 (CD276) research and …
B7-H3 (also known as CD276), a member of the B7 family of immune checkpoint proteins, is highly expressed in cancer cells and activated tumor-infiltrating immune cells, and helps …
Preclinical Efficacy of CD276 (B7-H3) CAR T in Acute Myeloid …
2024年11月5日 · We demonstrated potent and target specific efficacy of CD276 CAR T in an aggressive model of AML. As a tumor-specific antigen, CD276 represents an ideal therapeutic …
The Role of CD276 in Cancers - Frontiers
2021年3月25日 · Objective: Aberrant expression of the immune checkpoint molecule, CD276, also known as B7-H3, is associated with tumorigenesis. In this review, we aim to …
CD276 is an important player in macrophage recruitment into …
2021年7月21日 · Our data show a role for tumor-expressed CD276 on the macrophage recruitment into the tumor spheroid, and also in regulation of the extracellular matrix modulator …
mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells
2023年3月3日 · Here we show that high expression of the immune checkpoint B7-H3 (CD276) and high mTORC1 activity correlate with immunosuppressive phenotypes and worse clinical …
B7-H3/CD276: An Emerging Cancer Immunotherapy - PubMed
2021年7月19日 · B7 homolog 3 protein (B7-H3, also known as CD276), a newly identified immunoregulatory protein member of the B7 family, is an attractive and promising target for …