CD1（分化簇1）分为CD1a（R4），CD1b（R2），CD1c（R7），CD1d（R3）和CD1e（R2）五种。 它们与MHCⅠ类分子的结构相似，可以提呈脂质或者糖脂质的抗原。 另 …

CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.

CD分子，又称 分化簇 （Cluster of Differentiation）或分化群，也叫 白细胞分化抗原，是不同谱系的白细胞在正常分化成熟的不同阶段及活化过程中，出现或消失的细胞表面标记。 CD分子对 …

cd1a蛋白是一种跨膜蛋白，属于cd1家族，它在免疫系统中发挥重要作用。cd1家族包括cd1a、cd1b、cd1c和cd1d，它们与抗原呈递和t细胞免疫反应密切相关：与经典的主要组织相容性复 …

CD1 molecules present foreign and self lipids to diverse T cells and natural killer T (NKT) cells. Whereas the clonally restricted diverse T cells mediate adaptive immunity to microbial lipid...

本人cd抗原表是cd分子的完全指南。其中的列表中全面收录了从cd1到cd363靶标，并详细列举了各个靶标的别名，细胞表达和功能。使白细胞表面抗原分类一目了然。

cd1 (分化簇1）是分布于不同抗原提呈细胞（apc）表面的一类糖蛋白，在人类，其编码基因位于1号染色体。这类蛋白质分子与mhc1（第一类主要组织相容性复合体）有同源关系，参与将脂 …

CD1 molecules are cell surface glycoproteins expressed mainly by white blood cells, including B lymphocytes, macrophages and dendritic cells (DC). They consist of two chains: β 2 …

首先，CD代表cluster of differentiation，也就是说，大多数CD系列的蛋白和细胞分化信号有关。 CD1包括5个成员，和细胞的抗原递呈有关。 1a由T细胞，树突状细胞的部分亚群表达；1b介 …

The human cluster of differentiation (CD)1 system for antigen display is comprised of four types of antigen-presenting molecules, each with a distinct functional niche: CD1a, CD1b, CD1c, and …

Here, we summarize the molecular properties of the CD1 isoforms, their lipid antigens, and CD1-restricted T cells, with particular focus on CD1a. We then discuss the roles that CD1a-reactive …

This review summarizes the major features of CD1 genes and proteins, the patterns of intracellular trafficking of CD1 molecules, and how they sample different intracellular …

CD1 molecules are well known for their role in binding and presenting lipid antigens to mediate the activation of CD1-restricted T cells. However, much less appreciated is the fact that CD1 …

2017年10月30日 · The human cluster of differentiation (CD)1 system for antigen display is comprised of four types of antigen-presenting molecules, each with a distinct functional niche: …

2003年6月1日 · In this review we outline the functionally distinct subsets of CD1-restricted T cells and the pathways by which CD1-reactive T cells are activated and carry out their effector …

CD1 molecules are glycoproteins composed of a heavy chain noncovalently linked to beta-2 microglobulin (β 2 m), similar to MHC class I. Unlike MHC class I, however, CD1 molecules …

The CD1 proteins are a family of non-polymorphic, MHC class I-related molecules that present lipid antigens to subsets of T lymphocytes with innate- or adaptive-like immune functions. …

The CD1 molecules bind and present amphipathic lipid antigens for recognition by T-cell receptors. Here, we outline the recent advances in our understanding of how the processes of …

2024年6月4日 · Discover the crucial role of CD1 in the immune system. Learn how CD1 molecules present lipid antigens, aid in immune surveillance, and regulate responses to …

2022年12月13日 · We discuss new themes regarding antigen presentation by CD1 and MR1 and modes of antigen recognition by CD1- and MR1-restricted T cell receptors (TCRs). We …