CD30 is the target of the FDA approved therapeutic brentuximab vedotin (Adcetris). It is approved for use in: Hodgkin lymphoma (HL) (brentuximab vedotin) after failure of autologous stem cell …

CD30, also known as BerH2, Ki1 or TNFRSF8, is a transmembrane glycoprotein receptor that belongs to the tumor necrosis factor receptor (TNFR) and was first identified in Hodgkin …

CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well as a tumor …

2017年9月8日 · CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically expressed in certain hematopoietic malignancies, including anaplastic large …

CD30, a member of the tumor necrosis factor receptor superfamily, plays roles in pro-survival signal induction and cell proliferation in peripheral T-cell lymphoma (PTCL) and adult T-cell …

CD30 was originally described as a marker of Hodgkin's and Reed-Sternberg cells in Hodgkin's lymphoma. Cloning and characterization of cDNAs encoding CD30 and its ligand (CD30L) …

CD30 antigen, originally identified as a cell surface marker of the malignant Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin’s lymphoma by the use of the Ki-1 monoclonal antibody, is a …

CD30 refers to a TNFR-related surface protein that is expressed by activated T and B cells. It was originally identified as a marker for the tumor cells of Hodgkin's lymphoma. CD30 has also …

2017年9月8日 · CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically expressed in certain hematopoietic malignancies, including anaplastic large …

Several therapeutic strategies targeting CD30 have been developed, including monoclonal antibodies, conjugated antibodies (combination of brentuximab vedotin with chemotherapy or …

Knowing how much CD30 protein is on a patient’s cancer cells may help diagnose cancer and plan treatment. The CD30 protein is a type of tumor necrosis factor receptor and a type of …

CD30 is a protein made primarily by activated immune cells such as T cells and B cells. Some types of cancers that start from T cells or B cells, such as anaplastic large cell lymphom a and …

Cluster determinant 30 (CD30) has been recognized since the 1980s by a monoclonal antibody (Ki-1) as an epitope of a membrane protein highly expressed on Reed–Sternberg and …

2023年7月5日 · CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well …

2021年7月27日 · CD30 is expressed at relatively high rates of prevalence across a broad range of PTCLs and CTCLs. CD30 expression may be critical to the development of a subset of PTCLs …

CD30 has been identified as a marker on Reed–Sternberg cells in Hodgkin lymphoma and cells in other specific types of lymphoma. CD30 monoclonal antibodies may be used to treat …

CD30 is a cell surface receptor expressed in classical Hodgkin lymphoma (HL), anaplastic large cell lymphoma (ALCL), and many other lymphomas to a variable degree. It has been identified …

New for Spring 2025, the bracelet showcases the signature from the House's iconic B30 sneaker. The cable chain links in silver-finish brass are embellished with the openwork CD30 signature. …

In reactive lymphoid tissues, CD30 is a non-lineage-specific activation marker expressed by scattered B and T immunoblasts. Among PTCLs, strong and homogeneous CD30 expression …

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An Epstein-Barr virus-infected lymphoblastoid cell line (D430B) that grows in SCID-mice with the morphologic features of a CD30+ anaplastic large cell lymphoma, and is sensitive to anti …

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In this review, we describe current evidence for anti-CD30 therapy in lymphoma, discuss ongoing controversies and data gaps, and provide perspectives on the direction of anti-CD30 therapy …

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