The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome 11 (band 11q13). It is 13,388 base pairs long, and translates into 295 …

2024年12月24日 · CCND1 (Cyclin D1) is a Protein Coding gene. Diseases associated with CCND1 include Myeloma, Multiple and Von Hippel-Lindau Syndrome. Among its related …

2016年5月16日 · Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression …

2025年1月5日 · Clinical resource with information about CCND1, A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and …

2025年2月9日 · Atox1-cyclin D1 loop activity is critical for survival of tumor cells with inactivated TP53. MAT1A activation of glycolysis to promote NSCLC progression depends on stabilizing …

CCND1, the oncogene encoding cyclin D1, is amplified in a substantial proportion of human cancers. Although cyclin D1 overexpression has been reported in up to 50% of human breast …

CCND1 is a predictive biomarker for use of ibrutinib in patients. Mantle cell lymphoma and mature B-cell lymphoma/leukemia have the most therapies with CCND1 as a predictive biomarker.

2021年6月22日 · Marginal zone lymphoma (answer D) is negative for both CD5 and cyclin D1. Small lymphocytic lymphoma (answer E) is the main differential diagnosis for CD5 positive B …

The CCND1 gene encoding CCND1 is activated in B-cell lymphomas and overexpressed in many other human cancers (esophageal, lung, breast, bladder carcinomas, etc.) where it acts as a …

2023年4月6日 · Cyclin D1 (CCND1), a crucial mediator of cell cycle progression, possesses many mutation types with different mutation frequencies in human cancers. The G870A mutation is …