C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17. [5][6] CCL11 is a small cytokine belonging to …

CCL11 is a member of the eotaxin family that is chemotactic agents for eosinophils and participate in innate immunity. Eotaxins may exert physiological and pathological functions in the central nerve system, and CCL11 may induce neuronal cytotoxicity effects by inducing the production of reactive oxygen species (ROS) in microglia cells.

Eotaxin – or CCL11 – is another β-chemokine (CC chemokine) that is apparently involved in the pathogenesis of endometriosis.

Background: CCL-11 (eotaxin) is a chemokine with an important role in allergic conditions. Recent evidence indicates that CCL-11 plays a role in brain disorders as well. This paper reviews the associations between CCL-11 and aging, neurodegenerative, neuroinflammatory and neuropsychiatric disorders.

2022年6月12日 · CCL11 is a member of the eotaxin family that is chemotactic agents for eosinophils and participate in innate immunity. Eotaxins may exert physiological and pathological functions in the central nerve system, and CCL11 may induce neuronal cytotoxicity effects by inducing the production of reactive oxygen species (ROS) in microglia cells.

Chronic inflammation involves CCL11 and IL-13 to facilitate the development of liver cirrhosis and fibrosis in chronic hepatitis B virus infection. Chemoattraction of Neoplastic Glial Cells with CXCL10, CCL2 and CCL11 as a Paradigm for a Promising Therapeutic Approach for …

2024年12月24日 · CCL11 (C-C Motif Chemokine Ligand 11) is a Protein Coding gene. Diseases associated with CCL11 include Asthma and Human Immunodeficiency Virus Type 1. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include chemokine activity.

CCL11, also known as Eotaxin-1, is a protein secreted by various cells in the body, such as lymphocytes and monocytes, that plays a role in attracting immune cells and inducing inflammation, potentially contributing to neurological disorders like ASD. You might find these chapters and articles relevant to this topic. Junrui Ye, ... Naihong Chen.

2020年9月2日 · Background: CCL-11 (eotaxin) is a chemokine with an important role in allergic conditions. Recent evidence indicates that CCL-11 plays a role in brain disorders as well. This paper reviews the associations between CCL-11 and aging, neurodegenerative, neuroinflammatory and neuropsychiatric disorders.

2024年2月4日 · CCL11, a chemokine known for recruiting immune cells to the tumor microenvironment (TME), has an unclear role in the context of its expression, patient prognosis, and the presence of tumor-infiltrating immune cells (TILs) in breast cancer. The expression of CCL11 in invasive breast cancer (BRCA) was analyzed using TCGA database.