C2C12 is a myoblast cell line that is a subclone (produced by H. Blau, et al) of the mouse myoblast cell line established by D. Yaffe and O. Saxel. The C2C12 cell line differentiates …

The C2C12 cell model is a well-established in vitro system used to study muscle cell biology, including myogenesis (muscle formation), gene expression, and muscle metabolism. C2C12 …

2022年1月17日 · Intracellular metabolite profiles indicated that C2C12 myotubes cultured in serum and B27 had predominant glycolytic and oxidative metabolism, respectively, indicating …

2011年5月17日 · The cell line C2C12 is an immortal line of mouse skeletal myoblasts originally derived from satellite cells from the thigh muscle of a two month old female C3H mouse donor …

The C2C12 cell line, derived from mouse skeletal muscle myoblasts established by Yaffe and Saxel [22], is a common precursor cell model for skeletal muscle research, particularly in the …

2024年12月25日 · C2C12 (mouse myoblasts) is a subclone of a mouse myoblast cell line established by D. Yaffe and O. Saxel. C2C12 cells differentiate rapidly, readily forming …

In contrast, when C2C12 cells are stimulated with ligands or type I receptors, Smad5 is mainly observed in the nucleus [7]. These findings indicate that nuclear translocation induced by …

Mouse C2C12 muscle cells are the most commonly used cellular model to mimic skeletal muscle in vitro. Various studies reporting the effects of myostatin on C2C12 proliferation and …

We examined the myofibril biochemical, structural, and biophysical properties of C2C12, a mouse skeletal muscle cell line (American Type Culture Collection), to assess whether force …

2017年3月16日 · To verify the involvement of follistatin in myogenic differentiation and contractile force generation, we created genetically-engineered C2C12 cells capable of Dox-inducible …