
C1QBP - Wikipedia
The crystal structure of C1QBP at 2.25 Å resolution shows a homotrimeric ring displaying symmetry.The individual subunits are held together by noncovalent interactions and forms a doughnut shaped quaternary structure with a central cavity of 20 Å in diameter. Each Subunit of C1QBP has seven β-strand (β1- β7) and three α-helices (α1- α3). C1QBP is negatively …
C1QBP Gene - GeneCards | C1QBP Protein | C1QBP Antibody
2024年12月24日 · C1QBP (Complement C1q Binding Protein) is a Protein Coding gene. Diseases associated with C1QBP include Combined Oxidative Phosphorylation Deficiency 33 and Chanarin-Dorfman Syndrome. Among its related pathways are Signaling by Rho GTPases and Intrinsic Pathway for Apoptosis.
Complement C1q Binding Protein (C1QBP): Physiological …
Complement C1q binding protein (C1QBP, p32) is primarily localized in mitochondrial matrix and associated with mitochondrial oxidative phosphorylative function. C1QBP deficiency presents as a mitochondrial disorder involving multiple organ systems.
C1QBP regulates mitochondrial plasticity to impact tumor …
2022年11月16日 · Complement C1q binding protein (C1QBP) plays an indispensable role through regulating mitochondrial morphology, metabolism, and autophagy. C1QBP promotes mitochondrial plasticity to impact tumor metastasis and their therapeutic response.
Complement component 1q subcomponent binding protein in …
2019年3月14日 · Complement component 1q subcomponent binding protein (C1qbp) is a multifunctional protein involved in immune response, energy homeostasis of cells as a plasma membrane receptor, and a...
C1QBP complement C1q binding protein [ (human)] - National …
2025年2月9日 · C1qbp is upregulated in human lung and colon cancer cell lines and tumors. Overexpression of hyaluronan-binding protein 1 (HABP1/p32/gC1qR) in HepG2 cells leads to increased hyaluronan synthesis and cell proliferation by up-regulation of cyclin D1 in AKT-dependent pathway.
C1qbp complement component 1, q subcomponent binding protein …
2025年2月8日 · Mitochondrial C1QBP is essential for T cell antitumor function by maintaining mitochondrial plasticity and metabolic fitness. Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Entry - *601269 - COMPLEMENT COMPONENT C1q-BINDING PROTEIN; C1QBP …
2017年10月11日 · The C1QBP gene encodes an evolutionarily conserved and ubiquitously expressed multifunctional protein. It has been reported to be a predominantly mitochondrial matrix protein involved in inflammation and infection processes, mitochondrial ribosome biogenesis, regulation of apoptosis and nuclear transcription, and pre-mRNA splicing (summary by ...
C1QBP complement C1q binding protein [ Homo sapiens (human) ]
2024年1月7日 · A stable-isotope labeling by amino acids in cell culture coupled with mass spectrometry-based proteomics identifies downregulation of complement component 1, q subcomponent binding protein (C1QBP) expression by HIV-1 Vpr in Vpr transduced macrophages
Complement 1q-binding protein inhibits the mitochondrial …
We found that C1qbp overexpression could inhibit oxidative stress-induced MPT and cytotoxicity, whereas depletion of C1qbp had the opposite effect and instead sensitized the cells to MPT and cell death.