Pathology Outlines - CD117
2022年6月9日 · Also known as c-kit, stem cell factor receptor, mast cell growth factor (Appl Immunohistochem Mol Morphol 2005;13:205) Pathophysiology Has activating or gain of …
Pathology Outlines - Stains & CD markers
2025年3月4日 · Small intestine: chromogranin c-kit / CD117 DOG1 Ki67 synaptophysin Stomach: chromogranin c-kit / CD117 claudin 18.2 (pending) DOG1 desmin EBER1 / 2 / LMP gastrin …
Pathology Outlines - KIT
4 天之前 · KIT is the gene encoding a transmembrane tyrosine kinase receptor, involved in both the MAP kinase and AKT pathways, which are intimately involved with cell proliferation and …
Pathology Outlines - DLBCL, NOS
2024年9月18日 · Unfavorable prognostic features: Clinical: ↑ age, ↑ LDH, Eastern Cooperative Oncology Group (ECOG) ≥ 2, Ann Arbor stage III / IV, extranodal disease, bulky disease (J …
Pathology Outlines - Adenoid cystic carcinoma
2021年7月30日 · Other positive stains: c-KIT (CD117) MYB overexpression is a sensitive but nonspecific immunomarker for adenoid cystic carcinoma ( Am J Surg Pathol 2017;41:1422 ) …
Pathology Outlines - DOG1
2021年9月2日 · Monoclonal (SP31, K9, DOG1.1) and polyclonal antibodies (Cancer Control 2015;22:498) Most sensitive and specific marker for GIST
Pathology Outlines - Renal cell carcinoma (RCC)
2022年2月16日 · However, due to the lack of sensitivity and specificity and emerging utility for PAX8, CAIX, CK7 and CD117 (c-kit), RCC has become less commonly used by pathologists …
Pathology Outlines - Eosinophilic, solid and cystic
2021年5月25日 · Emerging subtype of renal cell carcinoma (RCC) with abundant eosinophilic cytoplasm and solid / cystic growth, not yet recognized in the 2013 International Society of …
Pathology Outlines - Oncocytoma
2020年9月21日 · Well circumscribed lesion; usually no pseudocapsule, tumor directly abuts the renal parenchyma (Am J Surg Pathol 1997;21:1, J Kidney Cancer VHL 2017;4:1)
Pathology Outlines - Cutaneous mastocytosis
2012年7月1日 · Leder (chloroacetate esterase), CD117 / c-kit. Differential diagnosis. Normal skin or dermatoses: