Your airways are lined with cells that create mucus. The mucus keeps your airways moist. It also traps bacteria, viruses, fungi and other particles to protect your lungs and prevent infection. …

The primary function of the bronchial epithelium is to act as a defensive barrier aiding the maintenance of normal airway function. Bronchial epithelial cells (BEC) form the interface …

In bronchial reserve cell hyperplasia, cells are arranged in cohesive sheets or clusters with nuclear overlapping and crowding. The nuclei reveal dark smudgy chromatin, inconspicuous …

2023年5月1日 · In the most proximal airway, hyaline cartilage rings support the larger respiratory passages, namely, the trachea and bronchi, to facilitate the passage of air. Three major cell …

2023年10月30日 · Bronchi are plural for bronchus and represent the passageways leading into the lungs. The first bronchi branch from trachea, and they are the right and left main bronchi. …

2016年8月7日 · Mucus cells disappear, ciliated epithelial cells decrease, and Clara cells increase as the terminal bronchiole is approached. Major cell types present in airway epithelium include …

2022年5月18日 · Primary human bronchial tracheal epithelial cells (HBECs) are a physiologically relevant system designed to improve respiratory studies and increase the success rate of …

Two airway cell types are critical for asthma pathogenesis: epithelial cells and smooth muscle cells. Airway epithelial cells, which are the first line of defense against inhaled pathogens and …

Bronchial epithelium lines the airway lumen and includes pseudostratified ciliated columnar epithelial cells, interspersed goblet cells and neuroendocrine cells, and underlying basal cells. …

This study will test the ability of primary human bronchial/tracheal epithelial cells (HBECs) to differentiate into mature airway tissue using an air-liquid interface (ALI) culture model.

2016年8月8日 · Normal human bronchial epithelial cells differentiated in the absence of HC (HC0) showed significantly less benzamil-sensitive short-circuit current than controls, as well as a …

We leveraged single-cell RNA-sequencing data sets to develop flow-cytometric panels to characterize and isolate the major airway epithelial subsets (basal, ciliated, and secretory …

2023年5月1日 · There are ten bronchopulmonary segments in each lung with their apex directed towards the hilum, and each is aeriated by a tertiary (segmental) bronchus [2]. The alveoli are …

2020年5月1日 · The human bronchial epithelium is an important barrier tissue that is damaged or pathologically altered in various acute and chronic respiratory conditions. To represent the …

Human bronchial epithelium has a number of mechanical functions, including mucociliary clearance and protection against noxious agents. Bronchial epithelial cells are also able to …

2022年9月27日 · Bronchi are the branches of the trachea which provide oxygen to the lungs. In cross-section, the bronchial wall appears similar to the trachea. Respiratory mucosa (or …

2021年9月16日 · A bronchiolovascular bundle, including terminal bronchiole, is located in the center of Miller's secondary lung lobule. A bronchiole lacks bronchial glands and cartilage.

2025年2月7日 · The nasal epithelium, as part of a continuous and integrated airway epithelium, provides a more accessible sample source than the bronchial epithelium. However, the …

2025年2月20日 · Blocking proteins YAP and TAZ in immune cells can reduce or reverse lung scarring in pulmonary fibrosis. These proteins, when inhibited, decrease inflammation by …

2023年8月8日 · Healthy human lung tissue is soft, light, and spongy. These characteristics facilitate and allow for elasticity and recoil for normal dynamic function. The lungs subdivide …

2025年2月7日 · A microscope image of lung cancer cells (purple) containing the activated form of a metabolic enzyme called GUK1 (brown) that supports cancer growth. Image: Haigis lab At a …

2025年2月20日 · Apr. 5, 2022 — Scientists have developed a treatment for pulmonary fibrosis by using nanoparticles coated in mannose -- a type of sugar -- to stop a population of lung cells …

This guideline provides recommendations on the use of radiation therapy to treat patients diagnosed with small cell lung cancer (SCLC). The guideline covers the appropriate use, …

In the large airways (2 0 to 2 5 branches), the major cells types are ciliated, undifferentiated columnar, secretory, and basal cells. In the small airways (2 6 to 2 23 branches), the cell types …

2025年2月19日 · Beamion LUNG-2 is a Phase III, open label, randomized, active-controlled study that is enrolling patients with unresectable or metastatic non-squamous non-small cell lung …

2025年2月5日 · Small cell lung cancer (SCLC) is an aggressive and heterogeneous subtype, representing 15% of lung cancer cases. Although SCLC initially responds to etoposide and …

2025年2月17日 · Patients with extensive-stage small cell lung cancer (ES-SCLC) saw significant survival benefits when treated with either PD-1 or PD-L1 inhibitors combined with …

IL-13 also directly induces proliferation of normal human airway epithelial cells (NHBE) cells, as reflected by tritiated thymidine uptake and cell counts in differentiated normal human bronchial …

Normal human bronchial epithelial cells differentiated in the absence of HC (HC0) showed significantly less benzamil-sensitive short-circuit current than controls, as well as a reduced …