Bretylium (also bretylium tosylate) is an antiarrhythmic agent. [1] It blocks the release of noradrenaline from nerve terminals. In effect, it decreases output from the peripheral sympathetic nervous system. It also acts by blocking K + channels and is considered a class III antiarrhythmic.

Bretylium is a norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias.

Apr 19, 2024 · Uses of Bretylium: It is used to treat certain types of abnormal heartbeats. What do I need to tell my doctor BEFORE I take Bretylium? If you are allergic to bretylium; any part of bretylium; or any other drugs, foods, or substances. Tell …

Medscape - Ventricular arrhythmias dosing for bretylium, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information....

Oct 15, 2020 · Bretylium, with an extensive pharmacologic and medicinal history, was approved by the United States Food and Drug Administration in 1986 for “short-term prevention and treatment of ventricular fibrillation (VF) and treatment of life-threatening ventricular arrhythmias and ventricular tachycardia (VT) unresponsive to adequate doses of a first ...

Feb 8, 2023 · Bretylium (bretylium tosylate) injection is an antiarrhythmic drug used in emergency medicine, cardiology, and other specialties for treatment of severely abnormal heart rhythm (ventricular fibrillation) and fast heartbeat (tachycardia). Bretylium has been discontinued, but generics may be available.

Dec 12, 2024 · Bretylium Injection package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

Dec 12, 2022 · What is this drug used for? It is used to treat certain types of abnormal heartbeats. What do I need to tell my doctor BEFORE I take this drug? If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the …

What Is Bretylium Tosylate and How Does It Work? Bretylium Tosylate is a prescription medication used to treat the symptoms of ventricular arrhythmia. Bretylium Tosylate is available under the following different brand names: Bretylium. What Are Side Effects Associated with Using Bretylium Tosylate?

Bretylium Tosylate Injection, USP is indicated in the prophylaxis and therapy of ventricular fibrillation.