Brainbow is a genetic cell-labeling technique where hundreds of different hues can be generated by stochastic and combinatorial expression of a few spectrally distinct fluorescent proteins.

2022年5月20日 · Brainbow is a technique of color-coding neurons in the brain to analyze the brain connectome. The neurons are tagged with a fluorescent protein and are allowed to express a fluorescent color corresponding to the loxP sites present in them.

2015年11月1日 · Originally developed to map neural circuits, today some scientists believe that the technique, called brainbow, is far better suited to other tasks, such as offering a closer look at what...

2013年5月5日 · The collection includes transgenic lines, plasmids and viral vectors with improved performance and added capabilities relative to the original Brainbow constructs.

2007年10月31日 · Neuronal circuits can now be seen in a multicolour 'brainbow'. A mix of 5 colours can produce about 90 distinct shades. Credit: Courtesy of the researchers. It's not often that research results...

2007年11月1日 · By activating multiple fluorescent proteins in neurons, neuroscientists at Harvard University are imaging the brain and nervous system as never before, rendering these cells in a riotous spray of colors dubbed a “Brainbow.”

2013年5月15日 · Led by Joshua Sanes and Jeff Lichtman, a group of Harvard researchers has made a host of technical improvements in the “Brainbow” imaging technique.

Their process is scientifically known as stochastic multicolor labeling, but it’s become popularly known as Brainbow. Since the groundbreaking first publication in Nature in 2007, Brainbow has become a vital tool in studying the brain, giving new

Brainbow is a genetic cell-labeling technique where hundreds of different hues can be generated by stochastic and combinatorial expression of a few spectrally distinct fluorescent proteins.

In a recently introduced transgenic multicolor labeling strategy called “Brainbow,” Cre-lox recombination is used to create a stochastic choice of expression among fluorescent proteins (XFPs), resulting in the indelible marking of mouse neurons with multiple, distinct colors.