In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

2023年3月17日 · The function of bone remodeling is to adjust the architecture to meet the changing needs of the body. Bone remodeling also helps to repair microdamage in the bone matrix, which prevents the accumulation of old bone. Additionally, bone remodeling aids in maintaining plasma calcium homeostasis.

Bone remodeling is carried out through the work of osteoclasts, which are bone cells that resorb bone and dissolve its minerals; and osteoblasts, which are bone cells that make the new bone matrix. Bones remodeling serves several functions.

Bone remodeling, continuing process of synthesis and destruction that gives bone its mature structure and maintains normal calcium levels in the body. Destruction, or resorption, of bone by large cells called osteoclasts releases calcium into the bloodstream to …

2022年4月16日 · Bone remodeling is required for repair of old damaged bone due to daily physical load and prevention of aging effects and its consequences. Impairment in the bone remodeling process often results in the progression to osteoporosis, a …

2022年7月18日 · Bone remodeling replaces old and damaged bone with new bone through a sequence of cellular events occurring on the same surface without any change in bone shape.

2025年1月5日 · Bone remodeling is the continuous lifelong coupled process of bone resorption and bone formation 1-4. It is the prerequisite for repairing bony microdamage during daily physical activities, the adaption of bone architecture to meet different mechanical demands and the prevention of aging effects and accumulation of old bone 2-4 .

Bone remodeling serves to adjust bone architecture to meet changing mechanical needs and it helps to repair microdamages in bone matrix preventing the accumulation of old bone. It also plays an important role in maintaining plasma calcium homeostasis.

2022年2月18日 · Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts.

The bone remodelling cycle replaces old and damaged bone and is a highly regulated, lifelong process essential for preserving bone integrity and maintaining mineral homeostasis. During the bone remodelling cycle, osteoclastic resorption is tightly coupled to osteoblastic bone formation.