Biotin is a coenzyme for five carboxylase enzymes, which are involved in the catabolism of amino acids and fatty acids, synthesis of fatty acids, and gluconeogenesis. [3] [4] Biotinylation of histone proteins in nuclear chromatin plays a role in chromatin stability and gene expression. [4] [8]

Biotin (vitamin B7) is a vitamin found in foods like eggs, milk, and bananas. Biotin deficiency can cause thinning of the hair and a rash on the face. Biotin is an important part of enzymes in the...

Mammals contain five biotin-enzymes that participate in a number of important metabolic pathways such as fatty acid biogenesis, gluconeogenesis and amino acid catabolism. All mammalian biotin-enzymes are post-translationally biotinylated, and therefore activated, through the action of a single HCS.

2024年3月31日 · Biotin, also known as vitamin B7, supports many parts of your body, including your nervous system, liver, eyes, hair, and skin. It helps the enzymes in your body carry out their jobs and keeps...

Biotin is a water-soluble vitamin and serves as a coenzyme for five carboxylases in humans. Biotin is also covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation.

2024年10月15日 · Taking supplements containing biotin can affect the accuracy of certain lab tests that diagnose a host of health conditions. Find out why and what to do about it.

Biotin is an essential micronutrient that acts as a co-factor for biotin-dependent metabolic enzymes. In bacteria, the supply of biotin can be achieved by de novo synthesis or import from exogenous sources.

Biotin enzymes are a family of enzymes ubiquitously found throughout nature. It appears that all organisms contain acetyl coA carboxylase, reflecting the essential role this enzyme plays in the synthesis of fatty acids required for membrane biogenesis.

Most biotin in foods is bound to protein, although some dietary biotin is in the free form [1,3,4,6]. Gastrointestinal proteases and peptidases break down the protein-bound forms of ingested biotin into biocytin and biotin-oligopeptides, which undergo further processing by biotinidase, an enzyme, in the intestinal lumen to release free biotin .

Biotin, a water-soluble vitamin, is used as cofactor of enzymes involved in carboxylation reactions. In humans, there are five biotin-dependent carboxylases: propionyl-CoA carboxylase; methylcrotonyl-CoA carboxylase; pyruvate carboxylase, and two forms of acetyl-CoA carboxylase.