Myc box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene. [5] [6] [7] This gene encodes several …

Dec 24, 2024 · BIN1 (Bridging Integrator 1) is a Protein Coding gene. Diseases associated with BIN1 include Myopathy, Centronuclear, 2 and Myopathy, Centronuclear, 1. Among its related …

The BIN1 gene provides instructions for making a protein that is found in tissues throughout the body, where it interacts with a variety of other proteins. Learn about this gene and related …

May 7, 2022 · The BIN1 locus contains the second-most significant genetic risk factor for late-onset Alzheimer’s disease. BIN1 undergoes alternate splicing to generate tissue- and cell-type …

Mar 9, 2023 · BIN1 is a tumor suppressor that regulates cancer development through a series of signals in tumor progression and microenvironment. It also makes BIN1 a feasible early …

Mar 18, 2020 · BIN1, one of the strongest genetic risk factors for late-onset Alzheimer’s disease, encodes a protein that dabbles in many cellular functions, taking a hand in Aβ production, tau …

Jan 1, 2017 · Bin1 encodes a set of BAR adapter proteins that bind and tubulate curved membranes in the cytosol and that can restrict gene expression in the nucleus. Bin1 protein …

Jul 29, 2020 · Identified as an Alzheimer’s disease (AD) susceptibility gene by genome wide-association studies, BIN1 has 10 isoforms that are expressed in the Central Nervous System …

Feb 27, 2025 · BIN1 overexpression inhibited cancer cell proliferation by promoting apoptosis and suppressed epithelial-mesenchymal transition (EMT), thereby reducing local invasion and …

Mar 26, 2021 · Shooting these smaller galaxies with short focal length lenses can be quite a challenge to get enough detail to produce a good image. These shots where done with a …