Basic fibroblast growth factor (bFGF) is a single chain polypeptide belonging to the heparin-binding growth factor family (Molloy et al., 2003). This growth factor has been shown to accelerate wound closure of patellar tendons, believed to be the result of increased fibroblast proliferation.

Sherman L., Stocker K.M., Morrison R., Ciment G. Basic fibroblast growth factor (bFGF) acts intracellularly to cause the transdifferentiation of avian neural crest-derived Schwann cell precursors into melanocytes.

Basic fibroblast growth factor (FGF)-2 has been shown to regulate many cellular functions including cell proliferation, migration, and differentiation, as well as angiogenesis in a variety of tissues, including skin, blood vessel, muscle, adipose, tendon/ligament, cartilage, bone, …

The benefit and role of basic fibroblast growth factor (bFGF) in scarless wound healing in clinical application and basic mechanism are discussed. bFGF is a glycoprotein which is widely used in treating wounds and ulcers. bFGF is easily applicable ...

Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis....

2023年3月24日 · Beyond the functions of the basic fibroblast growth factor (bFGF; FGF2) in biological processes, it also plays critical roles in the pathophysiological conditions promoting tumorigenesis .

2024年12月30日 · This article offers a comprehensive overview of the research and recent advances in various bFGF delivery systems, including hydrogels, liposomes, microspheres, and nanoparticles. Subsequently, the applications of bFGF pharmaceutical preparations in various fields are described.

FGF, also known as fibroblast growth factor, represents a family of approximately two dozen heparin-binding proteins that play pivotal roles in numerous cellular processes related to development and repair of tissues including brain, skin, and lungs.

2019年4月3日 · The Good: Basic Fibroblast Growth Factor and Cell Culture. There are many kinds of human FGFs (22 different kinds) , but one of the most commonly used in growing cells outside of the body is basic FGF (bFGF, also known as FGF2) (Fig. 2). This protein is widely used as a supplement when growing cells in vitro. Because cells grown on plastic are ...

Immortalized cortical cell line in the presence of growth factors bFGF (Cat. No. F0291) and EGF (Cat. No. E9644). Cultures are predominantly GFAP staining astrocytes (red) with a few β III-tubulin staining neurons (green). Counterstaining of cell nuclei with Hoechst dye.