Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint …

2024年12月24日 · BUB3 (BUB3 Mitotic Checkpoint Protein) is a Protein Coding gene. Diseases associated with BUB3 include Mosaic Variegated Aneuploidy Syndrome and Seckel Syndrome …

2022年5月18日 · Upregulation of the BUB3 gene has been found in a variety of human cancers and is associated with poor prognoses. Here, we review the structure and functions of BUB3 in …

Findings reveal a regulatory role of Bub3 in DMAP1-mediated DNA methylation upon mitotic stress. The roles for the BUB3-BUB1 complex in S phase. Small sequence differences in Bub1 …

2018年7月2日 · Our findings have uncovered a novel function of the plant BUB3 in MAP65-3-dependent microtubule reorganization during cytokinesis. Budding uninhibited by …

2016年5月5日 · Bub3 is a “donut-shaped” WD40 protein with a seven-blade β-propeller structure forming a symmetric circular wall around a central pore or funnel region ( 8, 9 ). It binds to …

2009年11月2日 · We propose that as a member of SAC, Bub3 is required for regulation of both meiosis I and II, and is potentially involved in kinetochore-microtubule attachment in …

2014年2月10日 · BuGZ binds to and stabilizes Bub3 during interphase and mitosis through a highly conserved GLE2p-binding sequence (GLEBS) domain.

2013年9月24日 · In this study, we report that Bub3, a 7-bladed β-propeller, is the MELT P reader. It contains an exceptionally well-conserved interface that docks the MELT P sequence on the …

2008年1月16日 · Using RNA interference and high-resolution microscopy, we analyzed K-MT interactions in Bub3-depleted cells and compared them to those in Bub1- or BubR1-depleted …