BRD2 Gene - GeneCards | BRD2 Protein | BRD2 Antibody
Dec 24, 2024 · BRD2 (Bromodomain Containing 2) is a Protein Coding gene. Diseases associated with BRD2 include Nut Midline Carcinoma and Adolescence-Adult Electroclinical …
BRD2 - Wikipedia
Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also …
靶向BET蛋白的药物发现——研究进展及新技术 - 知乎
BET家族蛋白包括BRD2(bromodomain-containing protein 2)、BRD3、BRD4以及睾丸特异性的BRDT(Testis-specific bromodomain-containing protein)，其结构具有相似性，包括N端的两个 …
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional ...
Brd2 interacts with the transcription factor Stat3 and the chromatin insulator CTCF-cohesin complex to support enhancer assembly, whereas Brd4 temporally controls RNA polymerase II …
生命学院季雄课题组揭示BRD2介导RNA聚合酶II转录的功能机理
Jun 25, 2022 · brd2/3/4/t是哺乳动物细胞中bet蛋白家族成员，它们均包含两个保守的溴结构域和一个et结构域，是多种疾病抑制剂的关键靶点。 BRD4通过招募转录延伸因子pTEF-b调控PolII的 …
BRD2 bromodomain containing 2 [ Homo sapiens (human) ]
Dec 10, 2024 · Title: BRD2 induces drug resistance through activation of the RasGRP1/Ras/ERK signaling pathway in adult T-cell lymphoblastic lymphoma. Bromodomain and extra-terminal …
北大生命学院季雄课题组揭示BRD2介导RNA聚合酶II转录的功能机 …
Jun 27, 2022 · 该研究阐明了brd2介导pol ii的转录起始和延伸事件，brd2与brd3在基因转录过程中的相互作用关系，以及brd2如何协调pol ii转录起始为干细胞分化的蓄势待 ...
BRD2 compartmentalizes the accessible genome - Nature
Apr 11, 2022 · Nature Genetics - BRD2 facilitates mixing and compartmentalization of active chromatin upon cohesin depletion. BRD2’s function is counteracted by cohesin and BRD4.
6046 - Gene ResultBRD2 bromodomain containing 2 [ (human)]
BRD2 mainly localizes in nucleus and BRD2 has distinct roles in initiating apoptosis. there are distinct functional roles for the two bromodomain proteins RING3/Brd2 and Brd4 in LANA …
靶向BET家族蛋白的药物开发 - 知乎 - 知乎专栏
BET的全称是bromodomain and extraterminal domain，BET家族蛋白共有4名成员，即BRD2、BRD3、BRD4、BRDT，其中BRD4有三种不同形式的剪切体。 RBET家族蛋白拥有两 …