BMP6 is able to induce all osteogenic markers in mesenchymal stem cells. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. BMPs are part of the transforming growth factor-beta (TGFB) superfamily.

2024年12月24日 · BMP6 (Bone Morphogenetic Protein 6) is a Protein Coding gene. Diseases associated with BMP6 include Iron Overload and Hemochromatosis, Type 1. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and …

In this review, we address the expression, function and regulation of BMP6 in various kinds of stem cells, with focus on mesenchymal stem cells (MSCs), germline stem cells (GSCs), hematopoietic stem cells (HSCs), and neural stem cells (NSCs).

2025年1月4日 · High BMP6 expression is associated with breast cancer. BMP6 plays a critical role in breast cancer cell aberrant proliferation and chemoresistance and may serve as a novel diagnostic biomarker or therapeutic target for breast cancer.

Bone Morphogenetic Protein 6 (BMP6) is one of the bone-inducing molecules that are deposited into the bone matrix and have osteoinductive activity. AI generated definition based on: Principles of Bone Biology (Third Edition) , 2008

2024年12月10日 · Title: Blood BMP6 Associated with Cognitive Performance and Alzheimer's Disease Diagnosis: A Longitudinal Study of Elders. Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique.

2025年2月8日 · Bmp6, Smad7, Id1, and Atoh8 transcripts are significantly modulated by the dietary iron content; BMP-6 also plays a physiological role in maintaining growth plate function; These results indicate that the BMP6 are differentially expressed in adult spinal cord and are up-regulated during EAE.