2024年12月24日 · BCL6 (BCL6 Transcription Repressor) is a Protein Coding gene. Diseases associated with BCL6 include Intravascular Large B-Cell Lymphoma and High-Grade B-Cell …

2022年12月2日 · B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the …

B cell lymphoma 6 (BCL6) is a conserved multi-domain protein that functions principally as a transcriptional repressor. This protein regulates many pivotal aspects of immune cell …

2023年8月3日 · BCL6 is a transcription factor located at 3q27 and is required for germinal center B cells formation and follicular helper T cells (TFH) differentiation

BCL6 is a transcriptional repressor that plays a role in the development of follicular helper T cells and splenic conventional dendritic cells (cDCs). It is not expressed in early hematopoietic …

BCL6 is required for GC B-cells to proliferate and tolerate the DNA damage that occurs as a byproduct of this process of immunoglobulin affinity maturation [1].

2022年12月2日 · B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the …

B-cell lymphoma 6 (BCL6) is a transcriptional repressor that regulates the differentiation of B lymphocytes and mediates the formation of germinal centers (GCs) by recruiting corepressors …

BCL6 is a transcriptional repressor which has emerged as a critical regulator of germinal centers (GC), the sites where B cells are selected based on the production of antibodies with high …

2023年10月20日 · Here, we found that BCL6 inhibits tumor-specific T term cell generation from T prog cell downstream of TCF1. We show that Bcl6 deficiency reduced the persistence of T …