BCL11B Gene - GeneCards | BC11B Protein | BC11B Antibody
Dec 24, 2024 · BCL11B (BCL11 Transcription Factor B) is a Protein Coding gene. Diseases associated with BCL11B include Intellectual Developmental Disorder With Speech Delay, …
Bcl11b—A Critical Neurodevelopmental Transcription …
B cell leukemia 11b (Bcl11b) is a zinc finger protein transcription factor with a multiplicity of functions. It works as both a genetic suppressor and activator, acting directly, attaching to …
Pivotal role of BCL11B in the immune, hematopoietic and ... - Nature
Mar 12, 2024 · The transcription factor BCL11B plays an essential role in the development of central nervous system and T cell differentiation by regulating the expression of numerous …
The transcription factor Bcl11b promotes both canonical and
Mar 12, 2021 · The BCL11B gene, encoding a transcription factor (TF) essential for T cell development and function, was the most extensively regulated, with expression increasing …
BCL11B , the Cerberus of human leukemia - American Society …
Sep 2, 2021 · Recent findings on lineage-promiscuous acute leukemia reveal the BCL11B locus as a multiheaded beast that can drive a variety of immature leukemias, including …
BCL11B mutations in patients affected by a neurodevelopmental …
Using massively parallel sequencing we identified 13 patients bearing heterozygous germline alterations in BCL11B. Notably, all of them are affected by global developmental delay with …
BCL11B BCL11 transcription factor B [ (human)] - National Center …
Feb 9, 2025 · BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activity. Endocannabinoid signalling in stem cells and …
BCL11B BCL11 transcription factor B [ Homo sapiens (human) ]
Dec 10, 2024 · Title: BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells. BCL11B Upregulates the Expression of RelA …
The T-ALL related gene BCL11B regulates the initial stages of
Feb 24, 2017 · Our studies show BCL11B is a key regulator of the initial stages of human T-cell differentiation and delineate the BCL11B transcriptional program, enabling the dissection of the...
BCL11B promotes T‐cell acute lymphoblastic leukaemia cell …
B‐cell lymphoma/leukaemia 11B (BCL11B) is an essential transcriptional regulator of T cells and is engaged in regulating vital biological processes including T‐cell development, proliferation, …
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