A beta-2 microglobulin (B2M) tumor marker test usually measures the amount of B2M in your blood. It can help find out how serious your cancer may be. Learn more.

Dec 24, 2024 · Complete information for B2M gene (Protein Coding), Beta-2-Microglobulin, including: function, proteins, disorders, pathways, orthologs, and expression.

Feb 11, 2021 · Beta-2 microglobulin (B2M), used as a tumor marker, is high in multiple myeloma or other types of cancer (lymphoma, leukemia, etc.).

Beta-2-microglobulin (B2M) is a protein that is found on the surface of almost all cells in the body and is shed by cells into the blood, particularly by B lymphocytes and tumour cells. It is present in most body fluids and its level rises with conditions that increase cell production and/or destruction, or that activate the immune system.

Aug 29, 2024 · Beta-2 microglobulin (B2M) is a cell surface protein that checks for cancer cell growth. It’s known as a tumor marker; it indicates that the cell is inflamed or performing abnormally. It can be found in blood or urine, and its discovery can indicate different diseases. When CLL cells replicate, they release B2M into the blood.

Mar 8, 2025 · Title: Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.

A serum beta-2-microglobulin (beta-2-M) value of less than 4 mcg/mL is a good prognostic factor in patients with multiple myeloma. In a study of pretreatment serum beta-2-M levels in 100 patients with myeloma, it was reported that the median survival of patients with values greater than 4 mcg/mL was 12 months, whereas median survival for patients with values less than 4 …

Oct 1, 2021 · B2M, an important subunit of the MHC class I molecule, has diverse functions in physiological and pathological conditions both in tumor cells and non-tumor cells, especially playing an important role in immune surveillance. B2M mutations have been identified in considerable cancer patients.

Nov 3, 2024 · Clinical resource with information about B2M, Familial visceral amyloidosis, Ostertag type, Hypoproteinemia, hypercatabolic, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

Apr 25, 2024 · The Beta-2 Microglobulin (B2M) blood test is an important diagnostic tool used to measure the level of beta-2 microglobulin in the blood. This protein, part of the major histocompatibility complex (MHC) class I molecules, plays a role in the immune system and can be elevated in certain diseases. Purpose of the B2M Blood Test