Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene. [5] [6]

Aug 1, 2022 · What Is the AXIN2 Gene? AXIN2 is a gene that you inherit from your parents. If you develop changes, or mutations, in this gene, it won’t function the way it should. If You Carry an …

Dec 24, 2024 · The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this …

This overview of clinical management guidelines is based on this patient’s positive test result for a pathogenic or likely pathogenic AXIN2 variant. Unless otherwise stated, medical management …

Sep 18, 2019 · The paralogous scaffold proteins axin and conductin/axin2 are key factors in the negative regulation of the Wnt pathway transcription factor β-catenin, thereby representing …

Jan 4, 2025 · The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene …

Feb 8, 2025 · The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene …

The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have …

Uniquely, AXIN2, but not AXIN1, is a transcriptional target of β-catenin-dependent Wnt signaling [34–36], and AXIN2 expression is elevated in cancers with activating Wnt pathway mutations.

The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have …