Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene. …

Dec 24, 2024 · ATRX (ATRX Chromatin Remodeler) is a Protein Coding gene. Diseases associated with ATRX include Alpha-Thalassemia Myelodysplasia Syndrome and Intellectual …

The ATRX gene provides instructions for making a protein that plays an essential role in normal development. Although the specific function of the ATRX protein is unknown, studies suggest …

ATRX is one of the most frequently mutated tumor suppressor genes in human cancers. ATRX protein is a chromatin remodeler and transcriptional regulator that is essential for normal …

ATRX (alpha-thalassemia mental retardation X-linked) is one of the most frequently mutated tumor suppressor genes in human cancers, especially in glioma, and recent findings indicate …

Jun 23, 2021 · Occurs in pediatric and adult high grade astrocytoma (Mod Pathol 2013;26:1425) Alternative Lengthening of Telomeres (ALT) is a non-telomerase mechanism of telomere …

Jan 25, 2024 · Stimulating the innate immune system has been explored as a therapeutic option for the treatment of gliomas. Inactivating mutations in ATRX, defining molecular alterations in …

Jun 23, 2021 · ATRX is a tumor suppressor that has been associated with protection from DNA replication stress, purportedly through resolution of difficult-to-replicate G-quadruplex (G4) …

Mar 7, 2023 · ATRX is a central player regulating the DNA damage response and prevents chromosomal instability. ATRX limits the formation of secondary structures that can trigger …

Jun 1, 2023 · ATRX is a central player regulating the DNA damage response and prevents chromosomal instability. ATRX limits the formation of secondary structures that can trigger …