ATF4 Gene - GeneCards | ATF4 Protein | ATF4 Antibody
2024年12月24日 · ATF4 (Activating Transcription Factor 4) is a Protein Coding gene. Diseases associated with ATF4 include Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis …
Biology of Activating Transcription Factor 4 (ATF4) and Its Role …
2022年4月1日 · Here, we review some important high-level concepts and questions concerning the basic biology of ATF4. We then discuss current knowledge and emerging questions about …
Biology of Activating Transcription Factor 4 (ATF4) and Its Role in ...
Activating transcription factor 4 (ATF4) is a multifunctional transcription regulatory protein in the basic leucine zipper superfamily. ATF4 can be expressed in most if not all mammalian cell …
Surviving Stress: Modulation of ATF4-Mediated Stress Responses …
Activating transcription factor 4 (ATF4) is a stress-induced transcription factor that is frequently upregulated in cancer cells. ATF4 controls the expression of a wide range of adaptive genes …
ATF4 in cellular stress, ferroptosis, and cancer
2024年2月21日 · Activating transcription factor 4 (ATF4), a member of the ATF/cAMP response element-binding (CREB) family, plays a critical role as a stress-induced transcription factor. It …
ATF4 activating transcription factor 4 [ (human)] - National Center …
2025年2月8日 · ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis. Activating transcription factor 4 regulates mitochondrial content, …
ATF4 is an oxidative stress–inducible, prodeath transcription …
In this work, we define a novel prodeath role for ATF4 in neurons in vitro in response to oxidative stress and in vivo in response to stroke, a condition linked to oxidative stress.
ATF4 Protects the Heart From Failure by Antagonizing Oxidative …
2022年5月16日 · ATF4 (activating transcription factor 4) is a common upstream transcription factor for multiple key enzymes of NADPH biosynthesis in both the cytosol and mitochondria. …
ATF4 activating transcription factor 4 [ Homo sapiens (human) ]
2025年1月4日 · Title: ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer. Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes …
ATF4 promotes angiogenesis and neuronal cell death and …
2017年5月29日 · Activating transcription factor 4 (ATF4) is a critical mediator of metabolic and oxidative homeostasis and cell survival. ATF4 is elevated in response to diverse …
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