Dec 24, 2024 · ASAH1 (N-Acylsphingosine Amidohydrolase 1) is a Protein Coding gene. Diseases associated with ASAH1 include Farber Lipogranulomatosis and Spinal Muscular …

ASAH1 expression is upregulated following radiation, suggesting it plays a role in conferring radioresistance to glioblastoma and in the development of recurrent glioblastoma. [10]

Mar 29, 2018 · ASAH1-related disorders comprise a spectrum that ranges from Farber disease (FD) to spinal muscular atrophy (SMA) with or without epilepsy. ASAH1-related disorders vary …

关于 asah1 Cytogenetic location: 8p22 Genomic coordinates (GRCh38): 8:18,055,992-18,084,961 (from NCBI) This gene has 68 transcripts (splice variants), 221 orthologues, 1 paralogue and …

Sep 24, 2024 · ASAH1（酸性神经氨酰酶1，acid ceramidase）是人类体内一个重要的酶，主要负 责水解神经酰胺生成神经酰胺和脂肪酸。 ASAH1参与多种生理过程，包括细胞代

Sep 25, 2018 · Here, we show that the acid ceramidase ASAH1, which controls sphingolipid metabolism, acted as a rheostat of the phenotypic switch in melanoma cells.

Feb 8, 2025 · ASAH1 inhibition synergistically sensitizes lung cancer cells resistant to the antiproliferative effect of choline kinase alpha inhibitors. Our results reveal a wide phenotypic …

The ASAH1 gene provides instructions for making an enzyme called acid ceramidase. This enzyme is found in lysosomes, which are cell compartments that digest and recycle materials. …

酸性神经酰胺酶(N—acylsphingosineamidohydrolase1,ASAH1)是鞘脂代谢的关键酶,其水解神经酰胺,生成鞘氨醇,继而代谢为鞘氨醇-1-磷酸(sphin-gosine-1-phosphate,S1P)。 神经酰胺是鞘磷 …

Dec 10, 2024 · Clinical resource with information about ASAH1, A genome-wide association study on obesity and obesity-related traits., Farber lipogranulomatosis, Spinal muscular atrophy …