Arsk (Russian: Арск, IPA:; Tatar: Арча) is a town and the administrative center of Arsky District in Tatarstan, Russia, located on the Kazanka River, 65 kilometers (40 mi) from the republic's capital of Kazan.

Dec 24, 2024 · ARSK (Arylsulfatase Family Member K) is a Protein Coding gene. Diseases associated with ARSK include Mucopolysaccharidosis, Type X and Mucopolysaccharidosis-Plus Syndrome. Among its related pathways are Sphingolipid metabolism and Metabolism of proteins.

Background: Human sulfatases play key roles in physiology and cause numerous pathological conditions upon deficiency/misregulation. Results: ARSK is ubiquitously expressed, localizes to lysosomes, and shows arylsulfatase activity at acidic pH. ...

Nov 30, 2018 · ArsK orthologs are widely distributed in arsenic-resistant bacteria and are phylogenetically divergent from the five reported arsenic efflux proteins, indicating that it may be a novel arsenic efflux transporter.

Arylsulfatase K (ARSK) is a recently characterised lysosomal hydrolase involved in GAG degradation that removes the 2-O-sulfate group from 2-sulfoglucuronate. Knockout of Arsk in mice was consistent with mild storage pathology, but no human phenotype has yet been described.

Dec 21, 2021 · Arylsulfatase K (ARSK) is a recently characterised lysosomal hydrolase involved in GAG degradation that removes the 2-O-sulfate group from 2-sulfoglucuronate. Knockout of Arsk in mice was consistent with mild storage pathology, …

Feb 8, 2025 · Arylsulfatase K, a novel lysosomal sulfatase. The identification, molecular cloning and initial characterization of three new members of this human gene family is reported. Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids.

ARSK A gene on chromosome 5q15 that encodes arylsulfatase K, a poorly characterised member of the sulfatase family.

Jun 17, 2024 · Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]). [supplied by OMIM, Mar 2008]

Dec 10, 2024 · Mice homozygous for a knock-out allele show moderate accumulation of heparan sulfate and chondroitin sulfate metabolites and signs of impaired social behavior and spatial …