
ARPC4 Gene - GeneCards | ARPC4 Protein | ARPC4 Antibody
2024年12月24日 · ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) is a Protein Coding gene. Diseases associated with ARPC4 include Developmental Delay, Language Impairment, And Ocular Abnormalities and Microcephaly. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and G-protein signaling RAC1 in cellular process.
ARPC4 - Wikipedia
Actin-related protein 2/3 complex subunit 4 is a protein that in humans is encoded by the ARPC4 gene. [5][6][7] This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution.
ARPC4 actin related protein 2/3 complex subunit 4 [ (human)]
2025年2月9日 · ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis. we show cell line-specific differences in ARP2/3 complex subunit dependency on cell migratory potential, and suggest ARPC4 to be one of the key members of the ARP2/3 complex in pancreatic cancer.
ARPC4 actin related protein 2/3 complex subunit 4 - NIH ...
2024年9月19日 · This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin.
ARPC4 actin related protein 2/3 complex subunit 4 [ Homo ...
2024年2月4日 · ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis. we show cell line-specific differences in ARP2/3 complex subunit dependency on cell migratory potential, and suggest ARPC4 to be one of the key members of the ARP2/3 complex in pancreatic cancer.
ACTIN-RELATED PROTEIN 2/3 COMPLEX, SUBUNIT 4; ARPC4
2022年11月29日 · The ARPC4 gene is a core subunit of the actin-related protein (ARP2/3) complex, which catalyzes the formation of F-actin networks (summary by Laboy Cintron et al., 2022). The Arp2/3 protein complex has been implicated in …
We report seven affected individuals from six families with a recurrent, de novo variant in the ARPC4 gene (c.472C>T [p.Arg158Cys (Gen-Bank: NM_005718.4)]). Core features in affected individuals include microcephaly, mild motor delays, and significant speech impair-ment.