AP-1 is another redox-sensitive transcription factor, which regulates cellular proliferation and differentiation during the neoplastic transformation [52]. AP-1 is composed of dimers between …

The dimeric transcription factor complex Activator Protein-1 (AP-1) is a group of proteins involved in a wide array of cell processes and a critical regulator of nuclear gene expression during T …

Here, we focus on the JUN and FOS proteins and aim to offer a new perspective on the molecular mechanisms that regulate the oncogenic and anti-oncogenic effects of AP-1 in tumour …

The AP-1 is a transcription factor belonging to the c-Fos, c-Jun, activating transcription factor (ATF) and Jun dimerization protein (JDP) families and controls a number of cellular processes …

AP-1 proteins are a versatile family of dimeric transcription factors. The activator protein-1 (AP-1) proteins are a collection of transcription factors characterized by the presence of a basic …

The Activator Protein-1 (AP-1) transcription factor (TF) family, composed of a variety of members including c-JUN, c-FOS and ATF, is involved in mediating many biological processes such as …

AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, …

2002年5月1日 · AP-1 proteins as regulators of cell death and survival. Apoptosis suppresses oncogenic transformation, and controls organogenesis and immune responses.

The transcription factor AP-1 (activator protein-1) is involved in cellular proliferation, transformation and death. Using mice and cells lacking AP-1 components, the target-genes …

2001年4月30日 · Recent studies using cells and mice deficient in individual AP-1 proteins have begun to shed light on their physiological functions in the control of cell proliferation, neoplastic...