Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system kills a target cell, whose membrane-surface antigens have been bound by specific antibodies. [1]

Antibody-dependent cellular cytotoxicity (ADCC) is a set of mechanisms that target cells coated with IgG antibodies of the proper subclasses (IgG1 in the human) to be the prey of cell-to-cell cytolysis executed by immune cells expressing FcRIIIA (CD16A).

2023年8月31日 · Antibody-dependent cellular cytotoxicity (ADCC) is a result of: Antibodies sticking infected cells and cancer cells to phagocytes. Antibodies sticking infected cells and cancer cells to cytotoxic T-lymphocytes (CTLs).

Antibody-Dependent Cellular Cytotoxicity (ADCC) is a crucial immune mechanism that bridges humoral and cellular immunity. In this process, antibodies mark infected or malignant cells for destruction by immune effector cells.

Antibody-dependent cellular cytotoxicity (ADCC) is an arm of the immune response initiated by antigen-bound antibody and effected by cells bearing the Fcγ receptor (e.g. NK cells, granulocytes, macrophages).

2014年1月1日 · Antibody-dependent cellular cytotoxicity (ADCC), also called antibody-dependent cell-mediated cytotoxicity, is an immune mechanism through which Fc receptor-bearing effector cells can recognize and kill antibody-coated target cells expressing tumor- or pathogen-derived antigens on their surface.

Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) refers to a process in which cells carrying Fc-receptors, along with other immune cells, cause damage to infected cells by binding to viral antigens and activating the complement system.

2014年1月1日 · Antibody-dependent cellular cytotoxicity (ADCC) is a mechanism mediated by different leukocyte populations bearing receptors for the Fc portion of immunoglobulins (FcRs) that enable them to kill a wide variety of antibody-coated target cells rapidly (Fanger et al. 1989).

Antibody-dependent cellular cytotoxicity (ADCC) is a mechanism mediated by different leukocyte populations bearing receptors for the Fc portion of immunoglobulins ( FcRs) that enable them to kill a wide variety of antibody-coated target cells rapidly (Fanger et al. 1989).

The effector function antibody-dependent cellular cytotoxicity (ADCC), investigated in this study, mediates NK cell killing of HIV-1 infected cells through the binding of antigen-antibody complexes to the FcγRIIIa receptor (CD16) expressed on NK cells .