Dec 24, 2024 · ANLN (Anillin, Actin Binding Protein) is a Protein Coding gene. Diseases associated with ANLN include Focal Segmental Glomerulosclerosis 8 and Genetic Steroid …

The ANLN gene in humans and the scraps gene in Drosophila encode Anillin. [5] In 1989, anillin was first isolated in embryos of Drosophila melanogaster. It was identified as an F-actin …

Feb 2, 2025 · ANLN enhances initiated Pol II clustering and promotes Pol II CTD phase separation. Short-term depletion of ANLN alters the chromatin binding and enhancer-mediated …

Feb 4, 2025 · 恶性肿瘤的发展基于癌细胞的快速分裂和增殖。Anillin （ANLN） 是一种有丝分裂蛋白，通过调控收缩环组装，促进细胞分裂。该团队于2023年发表了第一篇关于ANLN蛋白异常 …

Feb 9, 2025 · ANLN promotes carcinogenesis in oral cancer by regulating the PI3K/mTOR signaling pathway. Visualizing dynamic actin cross-linking processes driven by the actin …

Mar 17, 2022 · Anillin (ANLN) 是一种普遍表达的肌动蛋白结合蛋白，在细胞生长、迁移和胞质分裂中起着关键的促肿瘤作用。 大量研究表明，ANLN 在许多癌症类型中上调，并且与患者预后 …

Feb 21, 2025 · ANLN expression was found to negatively correlate with immune score and ESTIMATE scores, while positively correlating with tumor purity. This suggests that higher …

Feb 3, 2025 · Anillin（ANLN）作为一种有丝分裂蛋白，能与 F - 肌动蛋白、肌球蛋白 II 和 RhoA 等细胞骨架元件相互作用，调节细胞分裂，在有丝分裂中组织收缩环组件，推动有丝分裂进程 …

关于 anln Cytogenetic location: 7p14.2 Genomic coordinates (GRCh38): 7:36,389,862-36,453,791 (from NCBI) This gene has 13 transcripts (splice variants), 209 orthologues, 2 paralogues and …

Aug 3, 2021 · Exosomal ANLN-210 promoted macrophage polarization via PTEN/PI3K/Akt signaling pathway, thus stimulating tumor growth of HNSCC. ANLN was an independent …

Feb 28, 2025 · Anillin (ANLN) is an actin-binding protein responsible for cell motility and muscle cell contraction [6].It functions critically in various cellular processes, especially cytokinesis, …

Feb 2, 2025 · We find that nuclear ANLN directly interacts with the RNA polymerase II (Pol II) large subunit to form transcriptional condensates. ANLN enhances initiated Pol II clustering …

Jun 17, 2020 · Anillin (ANLN), an actin-binding protein, reportedly plays a vital role in cell proliferation and migration, particularly in cytokinesis. Although there have been findings …

Sep 20, 2022 · To provide a thorough perspective of ANLN’s roles among diverse malignancies, we conducted a comprehensive, pan-cancer analysis about ANLN, including but not limited to …

Jan 15, 2024 · Using unpaired and paired analyses, we examined ANLN expression in ccRCC tumour and normal samples (Fig. 1 B and C), and found that ANLN expression increased in …

Jan 15, 2024 · Abnormal anillin (ANLN) expression has been observed in multiple tumours and is closely associated with patient prognosis and clinical features. In this study, we systematically …

ANLN is a unique scaffolding protein that has been demonstrated to be an important factor in cell division, and it has a close relationship with major cytoskeletal structures. ANLN is usually …

Anillin (ANLN) is a unique scaffold protein that interacts with cytoskeletal elements such as F-actin, myosin II, and RhoA to regulate cell division 1,2. ANLN promotes mitotic progression by …

Anillin actin-binding protein (ANLN) is crucially involved in cell proliferation and migration. Moreover, ANLN is significantly in tumor progression in several types of human malignant …