2021年4月9日 · Acrania anencephaly sequence or acrania–exencephaly–anencephaly sequence is the progression from a relatively normal-appearing exposed brain due to an absent cranium (acrania) to an amorphous brain mass (exencephaly) to no recognisable brain tissue (anencephaly) 1.

2025年1月6日 · The acrania-anencephaly sequence explains the progression from acrania to exencephaly and then to anencephaly. Without a layer of protective meninges and a skull, the fetal brain protrudes outward and is exposed to amniotic fluid, known as exencephaly.

2023年3月8日 · Acrania is the absence of the fetal skull, which results in brain tissue being exposed to the amniotic fluid. It is thought that acrania is the precursor to anencephaly in what is called the acrania-exencephaly-anencaphaly sequence. Acrania can be …

Acrania and Anencephaly are both severe congenital birth defects that affect the development of the brain and skull. Acrania is characterized by the absence of the skull bones, while Anencephaly refers to the absence of a major portion of the brain and skull.

2020年11月7日 · Anencephaly is a lethal NTD in which there is a complete or partial absence of the cranium, cerebrum, cerebellum, and basal ganglia. Anencephaly is most commonly diagnosed during the first or second trimester of pregnancy using ultrasound, which can detect almost all cases of anencephaly.

2012年8月1日 · The term acrania has been used interchangeably with anencephaly in some parts of the world but that practice is discouraged as it confuses two very different conditions. Rarely, a layer of the amniotic sac separates to form a ribbon-like strip called an amniotic band.

Absence of cranial vault and cerebral hemispheres. At 12 weeks acrania is suspected by absence of the normally ossified skull and distortion of the brain (exencephaly). At >16 weeks the brain is destroyed (anencephaly). Chromosomal defects in isolated acrania are rare.

2023年8月29日 · Anencephaly is a fatal condition with a very poor outlook. Most fetuses with anencephaly pass away before birth, and the pregnancy ends in miscarriage. Almost all babies born with anencephaly die within a few minutes, hours or days.

Acrania is a rare congenital disorder that occurs in the human fetus in which the flat bones in the cranial vault are either completely or partially absent. [1] The cerebral hemispheres develop completely but abnormally. [1] The condition is frequently, though not always, associated with anencephaly. The fetus is said to have acrania if it ...

The study presents a pictorial essay of acrania-exencephaly-anencephaly sequence using two-(2D) and three-dimensional (3D) ultrasonography, documenting the different phenotypic characterization of this rare disease.