Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The ACAA2 gene encodes a 41.9 kDa protein that is composed of 397 amino acids and contains 88 observed peptides. [7][8] The encoded protein catalyzes the last step of the mitochondrial fatty acid beta oxidation spiral.

2024年12月24日 · ACAA2 (Acetyl-CoA Acyltransferase 2) is a Protein Coding gene. Diseases associated with ACAA2 include Disorder Of Keton Body Transport and Lipid Metabolism Disorder . Among its related pathways are Fatty acid metabolism and Metabolism .

2025年2月9日 · The oncogenic role and regulatory mechanism of ACAA2 in human ovarian cancer. ACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype. Negative correlation between acetyl-CoA acyltransferase 2 and cetuximab resistance in …

2023年10月5日 · Here, we report that ACAA2 is elevated in SCNCs and is a potential molecular indicator for SCNCs. ACAA2 expressions in tumour xenografts, tissue microarrays (TMAs), and patient tissues from...

Acetyl-CoAacyltransferase2 (ACAA2) is a key enzyme in the fatty acid oxidation pathway that catalyzes the final step of mitochondrial β oxidation, which plays an important role in fatty acid metabolism. The expression of ACAA2 is closely related to the occurrence and malignant progression of tumors. …

Here, we report that ACAA2 is elevated in SCNCs and is a potential molecular indicator for SCNCs. Methods: ACAA2 expressions in tumour xenografts, tissue microarrays (TMAs), and patient tissues from prostate and lung cancers were analysed via immunohistochemistry.

2024年11月3日 · Clinical resource with information about ACAA2, A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus., Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans., and available tests.

2023年1月1日 · ACSS2 is a bidirectional enzyme that can decompose acetyl-CoA to produce acetate when acetyl-CoA levels are excessive, thereby achieving a steady state of acetyl-CoA. PDC is found in the mitochondria and nucleus. PDC in mitochondria converts pyruvate to acetyl-CoA, which participates in TCA cycle.

2024年4月24日 · Acetyl-CoAacyltransferase2 (ACAA2) is a key enzyme in the fatty acid oxidation pathway that catalyzes the final step of mitochondrial β oxidation, which plays an important role in fatty acid metabolism. The expression of ACAA2 is closely related to the occurrence and malignant progression of tumors.

2025年2月25日 · ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor beta1. Data show that the major mitochondrial partner of Shc adaptor protein p46Shc is the lipid oxidation enzyme 3-ketoacylCoA thiolase ACAA2, to which p46Shc binds directly and with a …