ABCA2 Gene - GeneCards | ABCA2 Protein | ABCA2 Antibody
2024年12月24日 · ABCA2 (ATP Binding Cassette Subfamily A Member 2) is a Protein Coding gene. Diseases associated with ABCA2 include Intellectual Developmental Disorder With Poor …
ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target
The ATP binding cassette transporter ABCA2 is primarily an endolysosomal membrane protein that demonstrates pleiotropic functionalities, coalescing around the maintenance of …
The ABCA2 Transporter: Intracellular Roles in Trafficking and ...
ATP-binding cassette (ABC) transporters comprise a family of critical membrane bound proteins functioning in the translocation of molecules across cellular membranes. Substrates for …
ABCA2 ATP binding cassette subfamily A member 2 [ (human)]
2025年2月8日 · A possible biochemical mechanism links ABCA2 expression, amyloid precursor protein processing, and Alzheimer's disease. we demonstrate that ABCA2-deficiency inhibits …
Novel compound heterozygous ABCA2 variants cause IDPOGSA, a …
2024年1月17日 · The gene for ATP binding cassette subfamily A member 2 (ABCA2) is located at chromosome 9q34.3. Biallelic ABCA2 variants lead to intellectual developmental disorder with …
ABCA2 as a therapeutic target in cancer and nervous system
ABCA2, a transporter highly expressed in the cells of the nervous and haematopoetic systems, is associated with lipid transport and drug resistance in cancer cells, including tumor stem cells. …
ABCA2 ATP binding cassette subfamily A member 2
2024年11月2日 · Clinical resource with information about ABCA2, Intellectual developmental disorder with poor growth and with or without seizures or ataxia, and available tests. There are …
ATP-BINDING CASSETTE, SUBFAMILY A, MEMBER 2; ABCA2
2021年1月11日 · Members of the ABCA transporter subfamily, such as ABCA2, are involved in sterol transport (Ohtsuki et al., 2004). Luciani et al. (1994) identified 2 members of the ATP …
ABCA2: a candidate regulator of neural transmembrane lipid transport ...
Unlike other ABC A-subfamily members, ABCA2 is predominantly expressed in the brain and neural tissues. The unique expression profile together with available structural data suggest …
The ABCA subfamily—gene and protein structures, functions and ...
2006年4月4日 · ABCA2 expression colocalized in time and space with myelination markers (i.e., O4 and myelin basic protein) and appearance of thick myelin segments . Recent works …
- 某些结果已被删除