
AXIN1 Gene - GeneCards | AXIN1 Protein | AXIN1 Antibody
Dec 24, 2024 · AXIN1 (Axin 1) is a Protein Coding gene. Diseases associated with AXIN1 include Caudal Duplication Anomaly and Craniometadiaphyseal Osteosclerosis With Hip Dysplasia. …
AXIN1 - Wikipedia
Axin-1 is a protein that in humans is encoded by the AXIN1 gene. [5] This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a …
Wnt信号通路(主要基因/通路基因分类/信号通路图 - 知乎
Oct 11, 2023 · AXIN1和AXIN2基因编码Axin蛋白,是Wnt信号通路中另一个重要的负调节因子。 Axin蛋白能够与β-catenin和GSK-3β形成复合物,从而促进β-catenin的降解,抑制Wnt信号通 …
The scaffold protein AXIN1: gene ontology, signal network, and ...
Jan 30, 2024 · AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin signaling pathway, and subsequently unveiled its integral involvement across a diverse …
AXIN1 boosts antiviral response through IRF3 stabilization and …
Oct 9, 2024 · Here, we identify that AXIN1 acts as an effective regulator of antiviral innate immunity against both DNA and RNA virus infections. In the resting state, AXIN1 maintains the …
AXIN1 axin 1 [Homo sapiens (human)] - Gene - NCBI
Feb 8, 2025 · Title: Hypoxia exposure induces lactylation of Axin1 protein to promote glycolysis of esophageal carcinoma cells. UBE2N promotes cell viability and glycolysis by promoting Axin1 …
轴 1(AXIN1)基因 | MCE - MCE-生物活性分子大师
该蛋白作为无翼型 MMTV 整合位点家族成员 1 (Wnt) 信号通路的负调节因子发挥作用,可诱导细胞凋亡。 这种蛋白质的一部分的晶体结构,无论是单独的还是与其他蛋白质的复合物,都已得 …
支架蛋白 AXIN1:基因本体、信号网络和生理功能,Cell …
Jan 30, 2024 · 本文对哺乳动物 AXIN1 基因表达和蛋白质周转自首次发现以来的控制机制进行了复杂的探索,同时阐明了其在信号通路、组织发育和癌变调节中的重要性。 此外,我们还引入 …
Axis inhibition protein 1 (Axin1) Deletion-Induced ... - PubMed
Inactivating mutations of axis inhibition protein 1 (AXIN1), a negative regulator of the Wnt/β-Catenin cascade, are among the common genetic events in human hepatocellular carcinoma …
The scaffold protein AXIN1: gene ontology, signal network, and ...
Jan 30, 2024 · This review provides an intricate exploration of the mechanisms governing mammalian AXIN1 gene expression and protein turnover since its initial discovery, while also …