ASCL1 - Wikipedia
Achaete-scute homolog 1 is a protein that in humans is encoded by the ASCL1 gene. [5] [6] Because it was discovered subsequent to studies on its homolog in Drosophila, the Achaete …
ASCL1 Gene - GeneCards | ASCL1 Protein | ASCL1 Antibody
Dec 24, 2024 · ASCL1 (Achaete-Scute Family BHLH Transcription Factor 1) is a Protein Coding gene. Diseases associated with ASCL1 include Haddad Syndrome and Congenital Central …
ASCL1 activates neuronal stem cell-like lineage programming …
Apr 27, 2022 · We identify the proneuronal transcription factor ASCL1 motif to be enriched in hyper-accessible regions. ASCL1 acts as a driver of the lineage plastic, neuronal …
转录因子Ascl1可在脑内将胶质细胞转分化为神经元--中国科学院脑 …
Ascl1单一因子诱发的星形胶质细胞的转分化可在幼年脑（出生后两周）和成年脑中实现。 这一项研究成果建立了一种在体转分化高效获得功能性神经元的新方法，为实现疾病脑或创伤脑中在 …
achaete-scute 家族 bHLH 转录因子 1（ASCL1）基因 | MCE
该蛋白通过结合 E 盒 (5'-CANNTG-3') 激活转录。 有效的 DNA 结合需要与其他 BHLH 蛋白二聚化。 这种蛋白质在神经元的定型和分化以及嗅觉和自主神经元的产生中发挥作用。 在极少数情 …
Ascl1 Coordinately Regulates Gene Expression and the Chromatin ...
Mar 10, 2015 · The proneural transcription factor Ascl1 sequentially activates target genes in proliferating and differentiating progenitors during neurogenesis. Here Raposo et al. show that …
ASCL1 achaete-scute family bHLH transcription factor 1 [ (human)]
Feb 8, 2025 · ASCL1 regulates super-enhancer-associated miRNAs to define molecular subtypes of small cell lung cancer. REST Inactivation and Coexpression of ASCL1 and POU3F4 Are …
ASCL1 characterizes adrenergic neuroblastoma via its pioneer …
Dec 26, 2023 · ASCL1 represses the MES gene signature, but activates the ADRN gene signature via regulation of various signaling pathways and cooperation with other ADRN CRC …
Ascl1 / Mash1是中枢5-羟色胺能神经元发育所必需的。,Nature …
脊椎动物中中央血清素能（5-HT）神经元分化的转录控制最近受到了严格审查，已显示其涉及同源盒基因Nkx2-2和Lmx1b，Ets域基因Pet1（也称为Fev）和锌指基因Gata3。 基本的螺旋-环-螺 …
Proneural factors Ascl1 and Neurog2 contribute to neuronal …
May 13, 2019 · Ascl1 (also known as Mash1) and neurogenin 2 (Neurog2), which are the mammalian homologs of Drosophila achaete-scute complex and atonal genes, respectively, …