2022年6月22日 · The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ...

Diagnosis and classification of acute myeloid leukemia (AML) have significantly changed in 2022 with the newly proposed WHO 5th edition and International Consensus Classification (ICC) classification of hematopoietic neoplasms (subsequently referred to as WHO 2022 and ICC 2022 classification, respectively). 1,2 Both systems emphasize integration...

2002年10月1日 · Three unique subgroups of acute myeloid leukemia are recognized by the WHO classification (Table 1): (1) AML with recurrent genetic abnormalities, (2) AML with multilineage dysplasia, and (3) AML and MDS, therapy related. Cases that do not satisfy the criteria for any of these subgroups, or for which no genetic data can be obtained, should be ...

2016年5月19日 · Acute myeloid leukemia AML with recurrent genetic abnormalities The WHO continues to define specific acute myeloid leukemia (AML) disease entities by focusing on significant cytogenetic and molecular genetic subgroups.

2023年6月14日 · 急性髓性白血病(acute myeloid leukemia，AML)是造血系统异常的癌症，对人类健康存在巨大的威胁。在WHO造血淋巴肿瘤分类第五版(WHO-HAEM5)中，AML的分类进一步突出了遗传学定义的重要性，并在相关时不再强调原始细胞20%基数。

In the revised 4th edition of the WHO classification published in 2017 [3], AML is classified into 6 categories: AML with recurrent genetic abnormalities; AML with myelodysplasia-related changes (MRC); therapy-related myeloid neoplasms (t-MN); AML, not otherwise specified (NOS); myeloid sarcoma; and myeloid proliferations related to Down syndrom...

2023年12月1日 · For those interested in acute myeloid leukemia (AML), 2022 may be remembered as the year of reclassification. In 2022, the World Health Organization (WHO) published the 5th edition of their classification schema, while a separate system was published by a group of experts under the title of the International Consensus Classification (ICC) [ 1 ...

In 2016 a revision of the World Health Organization (WHO) classification of acute myeloid leukemia (AML) was introduced that included changes to several disease categories. The WHO approach results in disease categories that are defined by a combination of clinical, morphologic, immunophenotypic, an …

2025年1月31日 · Recent molecular and genetic developments have been integrated into the diagnostic criteria for AML in the fifth edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours and the 2022 International Consensus Classification (ICC) of Myeloid Neoplasms and Acute Leukemias, expanding the list of genetically defined ent...

1.病名 WHO-HAEM5将骨髓增生异常综合征 （myelodysplastic syndroms，MDS）改称为骨髓增生异常性肿瘤（myelodysplastic neoplasms，MDN），改名的因素，其一强调MDS是肿瘤性质，二是与骨髓增殖性肿瘤（MPN）的命名相一致。 鉴于MDN和MPN之间语音和语法相似，认为缩写MDS优于MDN而仍使用MDS。 2.病态造血 病态造血作为MDS 诊断 的重要指标而不是分类规则中的重要依据，在WHO -HAEM5取消了WHO-HAEM4R的MDS由原始细胞百分比、环形铁粒 …