ADAM17 - Wikipedia
A disintegrin and metalloprotease 17 (ADAM17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of …
ADAM17: a molecular switch to control inflammation and tissue ...
A disintegrin and metalloproteinase 17 (ADAM17), also known as tumor necrosis factor-α converting enzyme (TACE), is a membrane-bound enzyme that cleaves cell surface proteins, …
ADAM17与心血管疾病的相关性研究进展 - heartj.cn
ADAM17又称TNF-α转化酶（TNF-α converting enzyme，TACE）是一种去整合素-金属蛋白酶（a disintegrin and metalloproteases，ADAMs），通过对膜蛋白进行切割、使胞外片段从细胞膜表 …
Strategies to Target ADAM17 in Disease: From Its Discovery to …
For decades, disintegrin and metalloproteinase 17 (ADAM17) has been the object of deep investigation. Since its discovery as the tumor necrosis factor convertase, it has been …
金属蛋白酶在癌症中的免疫调节作用|ADAM17|MMPs|MMP9|蛋白 …
2023年1月12日 · 可溶性tnf-α通过蛋白水解酶adam17，也称为tnf-a转换酶（tace），从跨膜tnf-α（tmtnf-α）裂解，该酶可通过激活tnf-α来协调免疫和炎症反应。鉴于adam17对tnf信号通路的 …
新冠靶点新视角二： 跨膜蛋白酶ADAM17和TMPRSS2 - 知乎
AMAM17是一种参与多种蛋白质胞外域脱落的跨膜金属蛋白酶，具有黏附和蛋白水解特性，它可以使肿瘤坏死因子-α（TNF-α）前体转化为可溶性的TNF-α。 除了剪切TNF-α，该蛋白酶还在许 …
Targeting a disintegrin and metalloprotease (ADAM) 17-CD122
2024年6月26日 · Our findings reveal a critical post-translational regulation in CD8 + T cells, providing a potential therapeutic strategy of targeting ADAM17 for effective anti-tumor …
ADAM17: a molecular switch to control inflammation and tissue ...
2011年8月1日 · A disintegrin and metalloproteinase 17 (ADAM17), also known as tumor necrosis factor-α converting enzyme (TACE), is a membrane-bound enzyme that cleaves cell surface …
Immunomodulatory role of metalloproteinase ADAM17 in tumor …
2022年11月17日 · ADAM17 is a member of the a disintegrin and metalloproteinase (ADAM) family of transmembrane proteases involved in the shedding of some cell membrane proteins …
解整合素金属蛋白酶17(ADAM17)重组蛋白 - 百家号
2024年3月11日 · ADAM17是一种重要的蛋白酶，属于金属蛋白酶超家族，也被称为TNF-α转化酶，非常关键的参与细胞信号传导的调控。 ADAM17的全称为重组蛋白酶活性域蛋白，其特点 …
- 某些结果已被删除