Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene (named sprinter gene, …

Jun 20, 2022 · The ACTN3 gene controls fast-twitch muscle fibers, impacting power and endurance athletes. Check your genetic raw data.

ACTN3 is a gene that encodes for alpha-actinin-3, a protein expressed only in type-II muscle fibers (North et al., 1999). A common polymorphism in this gene is R577X (rs1815739), where …

Dec 24, 2024 · ACTN3 (Actinin Alpha 3) is a Protein Coding gene. Diseases associated with ACTN3 include Actn3 Deficiency and Bruxism. Among its related pathways are Sertoli-Sertoli …

ACTN3 genotype frequency in controls, elite sprint/power athletes, and endurance athletes.

Several investigations have found that α-actinin-3 deficiency due to XX homozygosity in the ACTN3 R577X polymorphism can negatively affect sports performance through several …

Dec 18, 2017 · One of the most promising genes in that regard is ACTN3, which has commonly been referred to as "a gene for speed". Recent research has examined the influence of this …

Feb 8, 2025 · ACTN3 is one of many genes contributing to genetic variation in muscle performance and adaptation to exercise. Data report the crystal structure of the actin binding …

Here, we show that α-actinin-3 plays a key role in the regulation of protein synthesis and breakdown signaling in skeletal muscle and influences muscle mass from early postnatal …

Dec 20, 2023 · Understanding the role of the actn3 gene can provide valuable information for athletes, coaches, and researchers working to optimize athletic training and performance. The …