
ABCG5 - Wikipedia
ATP-binding cassette sub-family G member 5 is a protein that in humans is encoded by the ABCG5 gene. [5][6][7] The protein encoded by this gene is a member of the superfamily of …
ABCG5/ABCG8 in cholesterol excretion and atherosclerosis
2014年1月20日 · ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of …
ABCG5 gene - MedlinePlus
The ABCG5 gene provides instructions for making sterolin-1, which makes up half of a protein called sterolin. Learn about this gene and related health conditions.
ABCG5 Gene - GeneCards | ABCG5 Protein | ABCG5 Antibody
2024年12月24日 · ABCG5 (ATP Binding Cassette Subfamily G Member 5) is a Protein Coding gene. Diseases associated with ABCG5 include Sitosterolemia 2 and Sitosterolemia. Among …
ABCG5/G8: a structural view to pathophysiology of the …
In this review, we summarize recent pathophysiological and structural findings of ABCG5/G8, interpret the structure-function relationship in disease-causing variants and describe the …
Sitosterolemia: Twenty Years of Discovery of the Function of ABCG5 ...
Sitosterolemia is a lipid disorder characterized by the accumulation of dietary xenosterols in plasma and tissues caused by mutations in either ABCG5 or ABCG8. ABCG5 ABCG8 …
Recent advances in ABCG5 and ABCG8 variants - PMC
In this review, we summarize the genetics and mechanisms of sitosterolemia and sterol trafficking, and provide an update on the understanding of the prevalence of ABCG5 and ABCG8 variants …
Identification of a gene, ABCG5 , important in the regulation of ...
The gene (called ABCG5) consists of 13 exons, and encodes a 651-residue, 70 kD protein with 6 putative membrane-spanning domains that contains the characteristic ABC signature motifs at …
ABCG5 ATP binding cassette subfamily G member 5 [ (human)]
2025年2月8日 · ATP-binding cassette (ABC) transporters G5 (ABCG5) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of …
Heterozygous ABCG5 Gene Deficiency and Risk of Coronary …
2020年8月30日 · For loss-of-function (LoF) variants at the ABCG5, ABCG8, PCSK9, or LDLR genes, relationship between impact on LDL (low-density lipoprotein) cholesterol (LDL-C) levels …