
ABCG2 - Wikipedia
ABCG2 is a translocation protein used to actively pump drugs and other compounds against their concentration gradient using the bonding and hydrolysis of ATP as the energy source. [1] …
ABCG2 gene - MedlinePlus
The ABCG2 gene belongs to a group of genes called the ATP-binding cassette family; genes in this family provide instructions for making proteins that transport molecules across cell …
ABCG2 Gene - GeneCards | ABCG2 Protein | ABCG2 Antibody
2024年12月24日 · ABCG2 (ATP Binding Cassette Subfamily G Member 2 (JR Blood Group)) is a Protein Coding gene. Diseases associated with ABCG2 include Uric Acid Concentration, …
PharmGKB summary: very important pharmacogene information for ABCG2
ABCG2, encoding the efflux pump BCRP, plays an important role in drug response and disposition. It is widely expressed and has a broad substrate specificity to efflux xenobiotics …
Inhibitors of Human ABCG2: From Technical Background to …
The ATP-binding cassette transporter G2 (ABCG2; also known as breast cancer resistance protein, BCRP) has been suggested to be involved in clinical multidrug resistance (MDR) in …
ABCG2 ATP binding cassette subfamily G member 2 (JR blood …
ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis. Adipocyte-rich microenvironment promotes …
Human ABCG2: structure, function, and its role in multidrug resistance ...
Human ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily and is known to contribute to multidrug resistance (MDR) in cancer chemotherapy. Among ABC …
The role of ABCG2 in health and disease: Linking cancer therapy ...
2025年1月1日 · ATP-binding cassette superfamily G member 2 (ABCG2), one of the ABC transporters, is necessary for the ATP-dependent efflux of several endogenous and …
Multidrug efflux transporter ABCG2: expression and regulation
2021年9月29日 · The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was originally discovered in a multidrug-resistant breast cancer cell line. Studies in …
The ABCG2 multidrug transporter is a pump gated by a valve and …
2019年11月28日 · The human ATP-binding cassette transporter ABCG2 is a key to anticancer resistance and physiological detoxification. However, the molecular mechanism of substrate …