2022年10月18日 · Alpha-1 is sometimes referred to as “genetic COPD” or “genetic emphysema.” Who does Alpha-1 affect? Alpha-1 antitrypsin deficiency affects people who have two copies …

Alpha-1 antitrypsin or α 1-antitrypsin (A1AT, α 1 AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene . A protease inhibitor , it is …

2024年8月17日 · Nelson DR, Teckman J, Di Bisceglie AM, Brenner DA. Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency. Clin Gastroenterol Hepatol. …

2024年3月21日 · Alpha-1 antitrypsin deficiency (A1AD) is a hereditary disorder characterized by low levels of a protein called alpha-1 antitrypsin (A1AT) which is found in the blood.

2006年10月27日 · Synonyms: AAT Deficiency, A1AT Deficiency, AATD, Alpha-1 Antiprotease Deficiency

2023年10月25日 · Alpha-1 antitrypsin (AAT) deficiency increases an individual’s risk for COPD. The deficiency is an inherited genetic condition with no cure. The resulting COPD would be …

Alpha-1 antitrypsin deficiency (AATD) is an inherited disease that causes an increased risk of having chronic obstructive pulmonary disease (COPD), liver disease, skin problems …

2023年12月13日 · What Is AAT Deficiency? Alpha-1 antitrypsin (AAT) deficiency is a condition that can cause serious lung or liver disease. Symptoms often include trouble breathing and …

A1AT is a large, 52‐kDa serum glycoprotein abundantly produced by the liver. It is a serine protease inhibitor whose primary function depends on its secretion from the liver and its …

2020年4月8日 · Alpha 1-antitrypsin (AAT) deficiency is one of the most common genetic diseases.Most persons carry two copies of the wild-type M allele of SERPINA1, which …