2-NBDG is a fluorescent glucose analog that has been used to monitor glucose uptake in live cells, as an indicator of cell viability. Although sensitive to its environment NBD fluorescence typically displays excitation/emission maxima of ∼465/540 nm and can be visualized using optical filters designed for fluorescein.

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry.

2005年9月30日 · The assay is based on direct incubation of mammalian cells with a fluorescent d-glucose analog 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-D-glucose (2-NBDG) followed by flow cytometric detection of fluorescence produced by the cells.

Among the most commonly used of these analogs are 2-NBDG and 6-NBDG, which contain a bulky 7-nitro-2,1,3-benzoxadiazol-4-yl-amino moiety in place of a hydroxy group on D-glucose. This fluorescent group significantly alters both the size and shape of these molecules compared to glucose, calling into question whether they actually enter cells by ...

2-NBDG是一种用于直接监测活细胞和组织对葡萄糖摄取活性的荧光标记葡萄糖类似物(λex=467nm，λem=542nm)，常用于葡萄糖摄入(Glucose uptake)实验。 Application 2-NBDG常作为评估细胞葡萄糖摄入的示踪物[2]；也可以用于肿瘤葡萄糖代谢检测[3]。

2-NBDG is a fluorescent glucose analog and it is used as an indicator for cell viability by monitoring glucose uptake in living cells (Zou et al.). 2-NBDG displays excitation and emission maxima at 465 nm and 540 nm, respectively (Yoshioka et al.).

The preliminary data clearly demonstrate a rapid uptake of 2-NBDG into tumor cells that can be monitored by fluorescence imaging analysis. The uptake displays saturation and competition with D -glucose, all properties expected for 2-NBDG uptake and retention in cancer cells.

Invitrogen™ 2-NBDG (2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose) 5 mg 2-NBDG is a fluorescent glucose analog that has been used to monitor glucose uptake in live cells, as an indicator of cell viability.

2-NBDG is a fluorescent glucose analog for visualizing glucose uptake into living cells. Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the …

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