2023年9月4日 · Metoclopramide is a dopamine receptor antagonist and has been approved by the FDA to treat nausea and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing gastric motility. It is also used to control nausea and vomiting in chemotherapy patients.

Metoclopramide is an antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.

Metoclopramide is a medication used to treat nausea, vomiting, gastroparesis, and gastroesophageal reflux disease. [5] It is also used to treat migraine headaches. [6] Common side effects include feeling tired, diarrhea, akathisia, and tardive dyskinesia. More serious side effects include neuroleptic malignant syndrome and depression. [5]

2020年2月17日 · Includes Metoclopramide indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.

2021年12月17日 · metoclopramide Mechanism of action dopamine (D2) receptor antagonist, which increases upper gastrointestinal motility, contractility, and lower esophageal sphincter tone, causing increased gastric emptying

Reglan tablets are indicated for the: • Treatment for 4 to 12 weeks of symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy. • Relief of symptoms ...

2020年7月23日 · ACEM Primary Pharmacology of Metoclopramide: the Pharmacokinetics; Pharmacodynamics; Clinical uses; Adverse effects

2024年3月5日 · Antiemetic; stimulant of upper GI motility (prokinetic agent); potent dopamine-receptor antagonist. Symptomatic treatment of acute and recurrent diabetic gastric stasis (gastroparesis).

The exact mechanism of action of metoclopramide in the treatment of gastroesophageal reflux and acute and recurrent diabetic gastroparesis has not been fully established. It seems to sensitize tissues to the action of acetylcholine.

2022年5月5日 · Reglan ODT (metoclopramide) is a "prokinetic" drug used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.