2021年4月7日 · Nocardia brain abscess occurs mostly in the fifth to sixth decades of life [10, 11], with the peak occurrence between ages 43 and 75 years. Purported risk factors for developing nocardial brain abscess include age, gender, and immunocompromised status [ 12 , 13 ].

Nocardial brain abscesses are a rare central nervous system infection with high morbidity and mortality. Infection is acquired through inhalation or direct innoculation and then spreads hematogenously.

2022年6月13日 · Central nervous system (CNS) nocardiosis is a rare infection that may affect both the brain and the spine in patients with immunodeficiency. CNS nocardiosis has been reported to represent ~2% of all cerebral abscesses, and to be present in 15-50% of patients with systemic infection 2-3.

2018年4月5日 · Nocardial brain abscesses are a rare but very severe infection that carries the high mortality rate, especially in immunocompromised patients. Early suspicion and confirmation of diagnosis are required to prevent morbidity and morality. Treatment includes surgical aspiration or excision combined with appropriate and prolonged antimicrobial therapy.

Immunocompetent individuals presenting with complicated and widespread Nocardia infection is an uncommon phenomenon. We describe an interesting case of a large Nocardia abscess in the brain in an immunocompetent patient that was aspirated.

2024年1月15日 · In this article, we present a series of Nocardia brain abscesses to elucidate pathological characteristics of brain nocardiosis in correlation with their neuroimaging and clinical features.

2024年5月2日 · Overall, 80% of nocardiosis cases present as invasive lung infection, disseminated infection, or brain abscess; 20% present as cellulitis. About 10% of cases with uncomplicated pneumonia are fatal. Fatality rates are even higher - up to 80 percent- for brain or central nervous system infections.

2021年4月7日 · Nocardia is an important cause of brain abscess in the immunocompromised host. Early diagnostic and therapeutic aspiration may help health care providers confirm the diagnosis, choose an appropriate antimicrobial regimen, and achieve source control.

CNS nocardiosis is an uncommon cause of brain abscess that is associated with significant morbidity and mortality for both immunocompromised and immunocompetent individuals. 1 - 3 Nocardia is a genus of gram-positive, weakly acid fast, aerobic bacteria found in soils worldwide, and the incidence of nocardiosis is increasing, presumably because o...

N. farcinica has the highest predilection for brain abscess formation of the 16 different Nocardia species. Nocardia species carry the highest morbidity and mortality of all brain abscesses necessitating prompt detection and intervention.