2021年3月12日 · miR-21 is clearly involved in key regulatory pathways. Modulating its expression in in vivo and in vitro studies show clear and important phenotype changes. We may ultimately …

The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of biological functions and diseases including development, cancer, cardiovascular diseases and …

2020年6月5日 · miR-21 has demonstrated its potential as a diagnostic biomarker for different types of cancer, such as breast, colorectal, and pancreatic cancers. In particular, Iorio et al. 56 …

2024年12月25日 · MIR21 (MicroRNA 21) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR21 include Glioblastoma and Oral Squamous Cell Carcinoma. …

In this review, we summarise the current knowledge of miR-21 functions in human disease, with an emphasis on its regulation, oncogenic role, targets in human cancers, potential as a …

2025年2月19日 · Title: miR-21 Exerts Anti-proliferative and Pro-apoptotic Effects in LPS-induced WI-38 Cells via Directly Targeting TIMP3. A miRNA-21-Mediated PTEN/Akt/NF-kappaB Axis …

Our results showed that miR-21 could act as a significant biomarker in the prognosis of various cancers. Further studies are warranted before the application of the useful biomarker in the …

2025年2月19日 · miR-21 contributes to the protection of delayed ischemic preconditioning against renal ischemia reperfusion injury in mice, which is at least in part mediated by targeting of …

2021年3月12日 · miRNA-21 is among the most abundant and highly conserved microRNAs (miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory …

The further use of miR-21 as a biomarker and target for cancer treatments is likely to improve the outcome for patients with cancer. The present review highlights recent findings associated with …