2024年12月25日 · WNT5B (Wnt Family Member 5B) is a Protein Coding gene. Diseases associated with WNT5B include Type 1 Diabetes Mellitus 4 and Fibular Aplasia Or Hypoplasia, Femoral Bowing And Poly-, Syn-, And Oligodactyly. Among its related pathways are ncRNAs involved in Wnt signaling in hepatocellular carcinoma and Wnt Pathway.

2022年5月1日 · WNT5B induces crosstalk between β-catenin-independent signaling and Wnt/β-catenin-dependent signaling. The Wnt signaling ligand WNT5B is implicated in various developmental pathways, both in normal and pathological physiology.

2021年7月23日 · WNT5B, a member of the WNT family of proteins that is closely related to WNT5A, is required for cell migration, cell proliferation, or cell differentiation in many cell types. WNT5B signals through the non-canonical β-catenin-independent signaling pathway and often functions as an antagonist of canonical WNT signaling.

2023年12月20日 · In zebrafish embryos, active complexes of Wnt5b and its membrane-bound receptor Ror2 are transported between cells via cellular protrusions called cytonemes to initiate paracrine Wnt5b...

Protein Wnt-5b is a protein that in humans is encoded by the WNT5B gene. [5][6] The WNT gene family consists of structurally-related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

2021年5月4日 · WNT5B, a member of the WNT family of proteins that is closely related to WNT5A, is required for cell migration, cell proliferation, or cell differentiation in many cell types. WNT5B signals through the non-canonical β-catenin-independent signaling pathway and often functions as an antagonist of cano …

These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the Wnt gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively.

2025年2月8日 · Gene target information for WNT5B - Wnt family member 5B (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

2024年10月1日 · WNT5B recruits DVL3 on the membrane to promote RAC1–PCP–JNK signaling. This pathway is a potential therapeutic target for non-small cell lung cancer. The WNT5B ligand regulates the non-canonical wingless-related integration site (WNT)–planar cell …

WNT5B的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为Wnt信号基因家族由结构相关基因，其编码分泌信号蛋白。