Wnt signaling pathway - Wikipedia
In cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors. The name Wnt, pronounced "wint", is a portmanteau created from the names Wingless and Int-1. [1]
Wnt/β-catenin signalling: function, biological mechanisms ...
2022年1月3日 · Wnt signalling plays an important role in the self-renewal of some tissues in mammals. For example, the Wnt signalling pathway is related to the development and renewal of...
Wnt signal transduction pathways - PMC - PubMed Central (PMC)
The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural patterning and organogenesis during embryonic development.
Wnt/β-catenin signaling: components, mechanisms, and diseases
We discuss Wnt ligands, agonists and antagonists and their interactions with Wnt receptors. We also dissect critical events that regulate β-catenin stability from Wnt receptors to the cytoplasmic β-catenin destruction complex, and nuclear machinery that mediates β …
The origin and evolution of Wnt signalling | Nature Reviews ...
2024年2月19日 · In this Review, we summarize the current state of research regarding the evolutionary origin of Wnt signalling, its ancestral function and the characteristics of the primal Wnt ligand, with...
Wnt/β-catenin signalling: function, biological mechanisms ...
Wnt signalling plays an important role in the self-renewal of some tissues in mammals. For example, the Wnt signalling pathway is related to the development and renewal of small-intestinal epithelial tissue and promotes the differentiation of Paneth cells at the base of the crypt.
Wnt signaling pathway: A comprehensive review - PubMed
Wnt signaling is an evolutionary cell-to-cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell and specification of n …