
WIF1 Gene - GeneCards | WIF1 Protein | WIF1 Antibody
2024年12月25日 · WIF1 (WNT Inhibitory Factor 1) is a Protein Coding gene. Diseases associated with WIF1 include Colorectal Cancer and Squamous Cell Papilloma. Among its related …
WIF1 - Wikipedia
WIF1 is a lipid -binding protein that binds to Wnt proteins and prevents them from triggering signalling. [6][7][8] WNT proteins are extracellular signaling molecules involved in the control …
WNT 抑制因子 1(WIF1)基因 | MCE - MCE-生物活性分子大师
这种蛋白质包含一个 Wnt 抑制因子 (WIF) 结构域和五个表皮生长因子 (EGF) 样结构域,并且被认为与中胚层分割有关。 该基因作为肿瘤抑制基因发挥作用,并已被发现在各种癌症中被表观 …
11197 - Gene ResultWIF1 WNT inhibitory factor 1 [ (human)]
2025年2月8日 · WIF-1 silencing due to promoter hypermethylation is an important mechanism underlying aberrant activation of the Wnt signaling pathway in carcinogenesis of the digestive …
WIF-1 蛋白与 WNT 蛋白关键结合,抑制其活性并调节 WNT 信号 …
2024年9月11日 · WIF-1 Protein, Human (HEK293, His) 是重组的 WIF-1 蛋白,由 HEK293 表达,带有 C-6*His 标签。 WIF-1 Protein, Human (HEK293, His) 全长 351 个氨基酸,分子量约 …
WIF-1研究进展 - 百度学术
WIF-1是Wnt信号通路上的拮抗物之一,可以阻断Wnt的经典通路和非经典通路.目前在人类多种肿瘤的研究发现WIF-1表达异常.WIF-1 (Wnt inhibitory factor-1),sFRP (Frizzled related protein) …
WIF-1 蛋白, Human (HEK293, His) | MCE - MCE-生物活性分子大师
WIF-1 protein critically binds to WNT protein, inhibits its activity and regulates the WNT signaling pathway. In addition to its inhibitory role, WIF-1 may also contribute to mesoderm …
心肌组织特异性过表达Wif-1转基因小鼠-
Wif-1通过直接与Wnt蛋白相连,从而阻止Wnt与受体蛋白复合物相连,使细胞质中的β-catenin由于磷酸化而不能积累,进而阻断了经典和非经典Wnt通路。 该转基因小鼠可用于Wif-1对心血管 …
WNT 抑制因子-1 (WIF-1):在致癌作用中的新作用?,Journal of …
2014年5月20日 · WIF-1 是 WNT 信号通路的生理抑制剂,用于预防因 WNT 信号通路激活而导致的致癌作用。 WIF 结构域的结构已知具有与 WNT 分子相互作用的结合位点,而其 EGF 样结构 …
WIF1 Antibody #2064 - Cell Signaling Technology (CST)
WIF1 (Wnt inhibitory factor 1) is a secreted protein that binds to Wnt proteins and inhibits their activity (1). It contains an N-terminal WIF domain and five EGF-like repeats (2). The WIF1 …