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Thyrotropin-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA) and a unique beta subunit (this protein) that confers specificity. [7] ^ "Human PubMed Reference:".

2024年12月25日 · TSHB (Thyroid Stimulating Hormone Subunit Beta) is a Protein Coding gene. Diseases associated with TSHB include Hypothyroidism, Congenital, Nongoitrous, 4 and Isolated Thyroid-Stimulating Hormone Deficiency. Among its related pathways are Peptide hormone metabolism and GPCR downstream signalling.

Thyroid stimulating hormone consists of two subunits called alpha and beta. The TSHB gene provides instructions for making the beta subunit. The alpha and beta subunits are bound together to produce the active form of the hormone.

Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and …

2022年1月31日 · Thyroid-stimulating hormone (TSH) is a noncovalently linked glycoprotein heterodimer and is part of a family of pituitary hormones containing a common alpha subunit (TSHA; see 118850) and a unique beta subunit that confers specificity (summary by …

2025年2月8日 · Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis.

Researchers have identified at least 10 TSHB gene mutations involved in congenital hypothyroidism, a condition characterized by abnormally low levels of thyroid hormones starting from birth.