Tumor Necrosis Factor-α Signaling in Macrophages - PubMed …
Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors.
TNF-α-producing macrophages determine subtype identity and
2021年11月15日 · We show that cJUN directly activates CCL2 via its enhancer regulatory element and recruits inflammatory macrophages to the TME of BL tumors, whereas JUNB …
- 作者: Mengyu Tu, Lukas Klein, Elisa Espinet, Theodoros Georgomanolis, Florian Wegwitz, Xiaojuan Li, Laura ...
- Publish Year: 2021
Macrophages in immunoregulation and therapeutics - Nature
2023年5月22日 · Herein, we discuss immune regulation in macrophage polarization and signaling, mechanical stresses and modulation, metabolic signaling pathways, mitochondrial and …
TGFβ reprograms TNF stimulation of macrophages towards a non …
2022年7月7日 · TGFβ priming reprograms the macrophage inflammatory response to TNF, switches macrophage cell fate towards osteoclasts, and enables TNF to fully induce osteoclast …
TNF-α-induced Regulation and Signalling in Macrophages
1996年10月1日 · Tumor necrosis factor α (TNF-α) is a pleiotropic cytokine produced predominantly by macrophages. In addition, macrophages respond to TNF-α by differentiating …
- 作者: David W.H. Riches, Edward D. Chan, Brent W. Winston
- Publish Year: 1996
TNF-α-producing macrophages determine subtype identity and …
TNF-α + macrophages force classical neoplastic cells into an aggressive phenotypic state via lineage reprogramming. Integration of ATAC-, ChIP- and RNA-seq data revealed distinct …
- 其他用户还问了以下问题
TNF-α and IL-12:a balancing act in macrophage functioning
2001年2月1日 · Tumor necrosis factor alpha (TNF-α) and interleukin 12 (IL-12) are two major macrophage-derived mediators of inflammatory responses in mammals. Increasing evidence …
TNF-alpha-induced regulation and signalling in macrophages
Tumor necrosis factor alpha (TNF-alpha) is a pleiotropic cytokine produced predominantly by macrophages. In addition, macrophages respond to TNF-alpha by differentiating to express …
TNF-a mediated inflammatory macrophage polarization ... - PubMed
The increased M2 macrophages could be beneficial for resolving inflammation and promoting tissue repair, confirmed by the histologic findings of appositional new bone formation around …
Neutrophils and macrophages drive TNF-induced …
2022年12月23日 · We present evidence of a role for the TRIFosome downstream of TNF-R1, independent of TLR3 or TLR4 engagement. Specifically, TNF-induced cell death and inflammation in murine macrophages were driven by the TLR4 …
